Can someone help me understand my test results?

laurenalex94

As I'm not able to determine what these results mean over the phone today (have to wait until appointment), can someone explain if they've had similar results or what it entails? It mentions the following:

FINAL DIAGNOSIS:
SIGMOID COLON POLYP, COMBINED LAPAROSCOPIC, ENDOSCOPIC POLYPECTOMY:
- INVASIVE, MODERATELY DIFFERENTIATED COLONIC ADENOCARCINOMA
INVADING INTO MUSCULARIS PROPRIA (pT2). SEE SYNOPTIC REPORT AND
COMMENT.
COMMENTS:
Immunohistochemistry (IHC) Testing for Mismatch Repair (MMR) Proteins - Results:

MLH1: Intact nuclear expression / MSH2: Intact nuclear expression
MSH6: Intact nuclear expression / PMS2: Intact nuclear expression
IHC INTERPRETATION (#): NO LOSS OF NUCLEAR EXPRESSION OF MMR PROTEINS;
LOW PROBABILITY OF MICROSATELLITE INSTABILITY-HIGH (MSI-H)#
# There are exceptions to the above IHC interpretation. These results should not be considered in isolation,
and clinical correlation with genetic counseling is recommended to assess the need for germline testing.
**NOTE: Non-neoplastic tissue / internal control demonstrate intact nuclear expression.
This case has been reviewed by a second pathologist (Dr. Tagliente), who is in essential agreement with the
final diagnosis.

SYNOPTIC REPORTS:
COLON AND RECTUM
SPECIMEN:
Specimen Integrity: Fragmented
TUMOR:
Tumor Site: Sigmoid colon
Histologic Type: Adenocarcinoma
Histologic Grade: G2, moderately differentiated
Size of Invasive Carcinoma: Cannot be determined - Arising in a large polyp that is fragmented. It appears to involve the majority of the (clinically) 5 cm polyp
Tumor Extent: Invades muscularis propria
Lymphovascular Invasion: Not identified
Tumor Bud Score: Low (0-4)
Type of Polyp in which Invasive Carcinoma Arose: Tubulovillous adenoma
Polyp Size: 5 cm (per surgeon’s Operative Report)
Polyp Configuration: Pedunculated with stalk (per Operative Report)
Stalk Length: Cannot be determined; Fragmented specimen - no clear stalk seen.
MARGINS:
Margin Status for Invasive Carcinoma: Cannot be determined; Fragmented. Tumor present at cauterized surface but
unclear if that is a true margin.
Margin Status for Non-Invasive Tumor: Cannot be determined; Fragmented.

SnapDragon2

Try posting your path report on colon talk.

smithdoor

This something you talked to youf doctor about.

It will a few cat/pet scans it will more clearer.

ENDOSCOPIC is limited in viewing.

I would look at blood test too.

That may tell more.

Dave