Help with building a watchful waiting gameplan
I am 3 weeks post-op for a right hemi-colectomy, with a Stage II, Grade 2 diagnosis. No spread to nearby organs visualized, and no involvement in 41 LNs resected, but there was LVSI seen in small vessel(s) but no large ones. So, T3N0. There was a single tumor, and it formed MSI-high (dMMR) and BRAF mutations, which, ironically (to me, anyway), seem to confer an improved prognosis for Stage II disease. I've been referred to a gastro/genetic specialist (Lynch has been ruled out) who I hope will agree that complete genomic testing is appropriate.
Because I also have chronic, recurrent uterine cancer, with /mildly disabling chemo-induced neuropathy, someone will have to do a really hard sell to convince me to do chemo. I read an old thread here and a few recent journal articles. The current consensus is there is none. For domeone with my results, it appears, at best, the conventional chemo regimen confers a less than 5% improvement in DFS or OS. 5FU seems to be useless alone (and the side effects seem unpleasant), and I will not take any more platin drugs given my current disability. I am a 70-year old female, and it's quality of life I value now. I am a reasonably fit and healthy person with no co-morbidities (except for cancer 🤣).
So, my strategy is watchful waiting. Other than imaging, which the surgeon wants to do semi-annually, and a yearly colonoscopy, as well as physician-guided diet and nutrition advice, I am a believer in the usefulness of rigorous bloodwork. That is my question for this Board.
Does anyone have suggestions based on their own "best practices" for bloodwork I should ask for?
Thanks for any feedback.
Best wishes, Oldbeauty
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