Hair loss and next week

Tueffel
Tueffel Member Posts: 327 Member
in Colorectal Cancer #1

So,

My Papa is loosing his hair now either due to the irinotecan or the avastin. It will be strange to come back. Papa already had thinning hair due to his age but now it will be more. It will be strange to see him again without hair, eyebrows or eyelashes. 

Otherwise Papa feels good. The MS is here and there but otherwise not so much. My Mama and he worked a little the last days before chemo will tire him out. Our cows are gone now. It is strange but I want them both to focus on life, their health and relax. Funny thing is that we have more money now as with the cows. Hard to wake up then if you work for nothing...

So, on Tuesday Papa has 2 MRIs, TACE and again chemo. Due to the fast growth they control the liver more now. It is no problem because MRI is only magnetic. After the TACE they check the liver for bleeding. I do hope that we can already see some good results. We would be devastated if they would still grow fast. I think we deserve some good news now. Nevertheless, the oncologist will do at least 4x folfiri. 

We might also have some results on the foundation one testing and the reevsluation of the last liver metadtases that got operated. My biggest fear is that it is normal colon cancer, then the next is that they cant treat it. But I also know that due to the foundation one testing, immunotherapy like keytruda might be an option even though Papa is MSS. 

So yeah we do all hope for something!

Tueffel

 

Comments

  • SnapDragon2
    SnapDragon2 Member Posts: 720 Member
    edited May 2021 #2
    I believe with MSS tumor

    I believe with MSS tumor burden is 8 or more for keytruda to be considered. 

    If he qualifies I will look for the paper I read about how keytruda and something else to synergize it for working longer.

  • DanNH
    DanNH Member Posts: 186 Member
    #3
    I read up on this treatment

    I read up on this treatment

    and made some notes in case we need to consider it in the future. I hope it helps your Papa. Thanks for sharing this new treatmen. 
    Dan

  • Tueffel
    Tueffel Member Posts: 327 Member
    edited May 2021 #4
    SnapDragon2 said:

    I believe with MSS tumor

    I believe with MSS tumor burden is 8 or more for keytruda to be considered. 

    If he qualifies I will look for the paper I read about how keytruda and something else to synergize it for working longer.

    Thanks

    I appreciate it when you send me the study/article then. For now we did not get the results back on the foundation one testing but I am hopeful that this way we might get another option.

    Still, we got good news. The TACE and chemo are working and the cancer is stable. When we got the news that the cancer grew 1mm a day you are so worried and anxious. Getting the news that during the last 2 weeks it did not get worse is a good start. Papa will have 3x more Folfiri now, that is the plan. I hope when Papa sees the oncologist that they also have some new info. But for now we have time and the doctors might got the control back. 

    Tueffel

  • Tueffel
    Tueffel Member Posts: 327 Member
    edited May 2021 #5
    DanNH said:

    I read up on this treatment

    I read up on this treatment

    and made some notes in case we need to consider it in the future. I hope it helps your Papa. Thanks for sharing this new treatmen. 
    Dan

    Yes do

    Yes do some research. Some people with MSS do qualify for keytruda and might benefit from it. I read about it in colon talk that they did foundation one or next genome sequencing and they got the okay to get it. So yes I hope that we will get this treatment option for the moment Folfiri might fail. Maybe it will be for your wife aswell?

    For now TACE and chemo are working. The cancer did not get worse and the TACE treated metastasis got apparently smaller. Now the doctors do have some time to figure things out, waiting for test results. I do hope the cancer stops growing for now.

    Tueffel

  • Real Tar Heel
    Real Tar Heel Member Posts: 307 Member
    edited May 2021 #6
    Tueffel said:

    Yes do

    Yes do some research. Some people with MSS do qualify for keytruda and might benefit from it. I read about it in colon talk that they did foundation one or next genome sequencing and they got the okay to get it. So yes I hope that we will get this treatment option for the moment Folfiri might fail. Maybe it will be for your wife aswell?

    For now TACE and chemo are working. The cancer did not get worse and the TACE treated metastasis got apparently smaller. Now the doctors do have some time to figure things out, waiting for test results. I do hope the cancer stops growing for now.

    Tueffel

    I read on colonclub a post

    I read on colonclub a post from a woman who had great success with keytruda and mss tumor with a burden of 10. We don't know the variables that made it successful though.

  • DanNH
    DanNH Member Posts: 186 Member
    edited May 2021 #7
    That's great news for your

    That's great news for your Dad!!!

     

  • Tueffel
    Tueffel Member Posts: 327 Member
    edited May 2021 #8
    Real Tar Heel said:

    I read on colonclub a post

    I read on colonclub a post from a woman who had great success with keytruda and mss tumor with a burden of 10. We don't know the variables that made it successful though.

    Unknown

    Yes, I agree we dont know what made it successful but I think if you have another treatment option after Folfiri it will help you with your mind. I think that is so important. I dont know if my dad will even qualify after foundation one testing, maybe we wont qualify or the effect will be not that successful but knowing that there isanother option when this chemo stops working? We all need some hope

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