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A reason to skip the Valentine's Day candy?

SandiaBuddy
SandiaBuddy CSN Member Posts: 1,381 Member
edited February 2019 in Colorectal Cancer #1

Recent article (abstract only) about dietary insulin load (high blood sugar/carbs) and recurrence in stage III: https://www.ncbi.nlm.nih.gov/pubmed/30726946

Evidence suggests that diets inducing postprandial hyperinsulinemia may be associated with increased cancer-related mortality. The goal of this study was to assess the influence of postdiagnosis dietary insulin load and dietary insulin index on outcomes of stage III colon cancer patients. . . High dietary insulin load had a statistically significant association with worse disease-free survival (DFS), comparing the highest vs lowest quintile (adjusted hazard ratio [HR] = 2.77, 95% confidence interval [CI] = 1.90 to 4.02, Ptrend < .001). High dietary insulin index was also associated with worse DFS (highest vs lowest quintile, HR = 1.75, 95% CI = 1.22 to 2.51, Ptrend= .01). The association between higher dietary insulin load and worse DFS differed by body mass index and was strongest among patients with obesity (HR = 3.66, 95% CI = 1.88 to 7.12, Pinteraction = .04). The influence of dietary insulin load on cancer outcomes did not differ by mutation status of KRAS, BRAF, PIK3CA, TP53, or microsatellite instability. . . Patients with resected stage III colon cancer who consumed a high-insulinogenic diet were at increased risk of recurrence and mortality. These findings support the importance of dietary management following resection of colon cancer, and future research into underlying mechanisms of action is warranted.

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Comments

  • Trubrit
    Trubrit CSN Member Posts: 5,808 Member
    #2
    And yet.....

    I will continue to enjoy my chocolates. 

    I'm hoping for Pecan Delights. I've taken quite a liking to them. 

    Tru

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  • Butt
    Butt CSN Member Posts: 352 Member
    edited February 2019 #3

    If I were following all those advises I would have been admitted to the nut house long time ago.........

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  • Annabelle41415
    Annabelle41415 CSN Member Posts: 6,744 Member
    #4
    Chocolate

    My downfall isn't so much chocolate as it could last me a long while, but if you add sea salt to it, I'm game.  My weakness has always been salt which isn't good for you at all.  Put the two together and I'll eat it.

    Kim

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