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CAR-T or TCR-T for late stage ovarian cancer

tanguylam
tanguylam CSN Member Posts: 1
in Ovarian Cancer #1

My sister was diagnosed of ovarian cancer IIIC in Jan 2014 and had a successful operation followed by platinum based chemo treatments. However, the cancer came back 1.5 years later and becomes platinum resistant after two relapses. Her current health status won't allow for further chemo treatment and latest CA125 counts reach 500+. As her brca test is negative, she may not get good results by taking Olaparib or Niraparib. I wonder what options are still available for late stage OC patients. I heard CAR-T or TCR-T trials may help. However, they are more effective for hematological tumors than for solid tumors. Should my sister participate in CAR-T or TCR-T trials?

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  • Tethys41
    Tethys41 CSN Member Posts: 1,383 Member
    edited June 2018 #2
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    Hi tanuylam

    I'm sorry to hear about your sister.  Unfortunately, I don't know anyting about the TCR-T or CAR-T trials. 

    Has she asked her doctor about them?  

    She may want to check into this program:    careoncology.com

    or look into this doctor's approach:    www.bruckneroncology.com

    You can also see if there are any other applicable clinical trials at:  clinicaltrials.gov

    I hope she finds something that works for her.

    Good luck.

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