PolyPEPI1018 trial (cancer vaccine)

Mikenh
Mikenh Member Posts: 777
in Colorectal Cancer #1

This is an immunotherapy trial for Tumor Infiltrating Lymphocytes targetting common CRC cancer genes. My guess is that this is follow-on work from NCI. This could be incredibly exciting stuff as this could cure common KRAS mutations in CRC. My guess is that it could cure other types of cancer as well with these mutations. I'm guessing the G12D and G12V are covered. I think that six mutations are covered overall and I don't know which the others would be.

 

https://clinicaltrials.gov/ct2/show/NCT03391232

Comments

  • Mikenh
    Mikenh Member Posts: 777
    #2
    There's another similar

    There's another similar vaccine in trials in South Korea.

  • darcher
    darcher Member Posts: 304 Member
    #3
    Sounds good.

      A cancer vaccine would have been great to have a few years back before this mess started.  If it's a cure and doesn't do the damage chemo and radiation does it's worth it's weight in gold.

  • Mikenh
    Mikenh Member Posts: 777
    #4
    darcher said:

    Sounds good.

      A cancer vaccine would have been great to have a few years back before this mess started.  If it's a cure and doesn't do the damage chemo and radiation does it's worth it's weight in gold.

    I think that these vaccines

    I think that these vaccines are fairly narrow in the gene mutations that they target but I think that they target the most common ones.

  • kyolcu
    kyolcu Member Posts: 111
    #5
    Vaccine

    Thanks for postings. Has anyone heard about vaccine in Israel. I read it somewhere but I don’t have updated information. Please let us know, if you guys heard anything about it. I believe they started trials in human this year.

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