Finally got the second neoadjuvant C-125 results

evolo58

First one after the baseline, which was 121.6. It's now down to 43.7 after the first chemo treatment. Hopefully, the third treatment brings me even further down. So even if my fibroids are causing problems, I guess they're not causing THAT much of a problem.

HOPEFULLY, between the third one and a hopefully-improved second CT scan (though I still would like a different tech reading it because I really don't trust that first one), I'll be good to go for surgery in February or so (I'm on neoadjuvant treatment for clinically-diagnosed stage 4B UPSC: three chemos before, three after) ... and much more hopefully, an optimal debulking. Not that it's a magic potion, but I need every positive outcome I can get! One problem with neoadjuvant is the waiting game. You KNOW you still have this .... thing ... in you, and you want it OUT already, darn it! 

UPSC and its Type II friends are not only really worrisome ... they seem to still puzzle doctors today. The problem can be a mass or a tiny speck. They usually affect women of a certain age and type ....except when they don't. UPSC can be pure or mixed. Some studies suggest a mixed serous has a better outcome than pure if the troublesome Type II is under a certain percentage (25%, I believe), but many don't, but none of them have a large enough sample to make a more definitive conclusion. The Type IIs have no pattern, and since the Type IIs are the ones that often get short-changed in studies, even though they cause at least 40% of all UC deaths, there isn't nearly enough research on them, and much of it is pretty old. Ugh. 

But for now, I am pleased with the C-125 result this time. As my onco nurses keep remnding me, one step at a time.

Jairoldi

That's great

Those numbers are certainly headed in the right direction. Every bit of positive news is welcome news!I

I agree, this UPSC diagnosis feels like an extra whammy.