Selinexor for Relapsed/Refractory Multiple Myeloma
Options
AllSurvivors
CSN Member Posts: 8
recent news item - Patients with relapsed/refractory multiple myeloma (RRMM) for whom prior treatment with lenalidomide, pomalidomide, bortezomib, and carfilzomib fail have few treatment options. Selinexor (KPT-330) is a selective inhibitor of nuclear export (SINE) under development for the treatment of RRMM and other advanced hematologic malignancies. Selinexor induces cell death through apoptosis and autophagy. This dual mechanism is both novel and potentially synergistic with mechanisms already acted upon by drugs used in the treatment of patients with RRMM. (source: mmdevelopments.org)
0
Discussion Boards
- All Discussion Boards
- 6 CSN Information
- 6 Welcome to CSN
- 122.4K Cancer specific
- 2.8K Anal Cancer
- 454 Bladder Cancer
- 310 Bone Cancers
- 1.6K Brain Cancer
- 28.6K Breast Cancer
- 406 Childhood Cancers
- 27.9K Colorectal Cancer
- 4.6K Esophageal Cancer
- 1.2K Gynecological Cancers (other than ovarian and uterine)
- 13K Head and Neck Cancer
- 6.4K Kidney Cancer
- 680 Leukemia
- 800 Liver Cancer
- 4.2K Lung Cancer
- 5.1K Lymphoma (Hodgkin and Non-Hodgkin)
- 241 Multiple Myeloma
- 7.2K Ovarian Cancer
- 69 Pancreatic Cancer
- 493 Peritoneal Cancer
- 5.6K Prostate Cancer
- 1.2K Rare and Other Cancers
- 544 Sarcoma
- 742 Skin Cancer
- 659 Stomach Cancer
- 192 Testicular Cancer
- 1.5K Thyroid Cancer
- 5.9K Uterine/Endometrial Cancer
- 6.4K Lifestyle Discussion Boards