Stage II chemo decision - MSI-H and ONCOTYPE-DX

Brajesh
Brajesh Member Posts: 10
in Colorectal Cancer #1

Hi,

I recently posted about my dad being in stage II grey zone where its not clear chemo would be helpful.  After reading a bit I found that there are two tests that can help make a better decision in this situation.

One test is the MSI-H (microasatellite instability H) and the other is ONCOTYPE-DX.

Has anyone had these tests done?

Comments

  • Joan M
    Joan M CSN Member Posts: 409 Member
    #2
    I had the MSI test

    I don't remember hearing about ONCOTYPE.  I was tested for the MSI, BRAF, and KRAS.  I  have the KRAS mutation, no MSI. 

    They use these tests because it will help them determine which medicines to use for chemo.   

    Hope your dad is doing well.

    Merry Christmas,

    Joan

  • kmygil
    kmygil CSN Member Posts: 876 Member
    #3
    Tests

    I had tests done and was found to have HNPCC (Lynch Syndrome) which is essentially an MIS, but the chemo protocol was about the same as for non-HNPCC colon cancer.  I would go ahead and have the tests done so the chemo targeting is more efficient.

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