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PPI

dodger21
dodger21 CSN Member Posts: 85 Member
in Kidney Cancer #1

Just curious if anyone here has got kidney cancer from years of PPI use (proton pump inhibitors for reflux)?

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Comments

  • Talmidah
    Talmidah CSN Member Posts: 25
    #2
    That would be yes, unfortunately

    Dodger21 - Add me to the list of people who developed RCC after 15 plus years of uninterupted PPI use.  I was diagnosed with GERD a long time ago and took just about every medication, changed my diet, and still showed no improvement.  I even continued to take them after my renal CA diagnosis.  Only a endoscopy/colonoscopy a few months after my partial nephrectomy revealed I had both celiac and gastritis (not what you expect after years on PPIs). Once my celiac symptoms were addressed through a gluten free diet, I lost weight and my GERD has improved.   The evidence supporting a connection between long-term PPI use and kidney CA is real and growing.  Patients who have been on PPIs or antacids for more than a year and still have symptoms need to check out other reasons.  Be persistent.

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  • dodger21
    dodger21 CSN Member Posts: 85 Member
    #3
    Thanks

    hi Talmidah,

     

    thanks heaps for replying. This is all new to me sorry, so could you explain what RCC stands for?

     

    i feel a bit bummed that in 2011 I was diagnosed with Barrett's oesophagus with low grade dysplasia, which is pre cancerous cells. I was told the only way to prevent it becoming full blown cancer was to take PPI s for the rest of my life.  Well, 5 years down the track and I'm still on them and now this! 

    Preventing cancer in one pre cancerous organ leads to cancer in another! Go figure!

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  • Footstomper
    Footstomper CSN Member Posts: 1,237 Member
    #4
    dodger21 said:

    Thanks

    hi Talmidah,

     

    thanks heaps for replying. This is all new to me sorry, so could you explain what RCC stands for?

     

    i feel a bit bummed that in 2011 I was diagnosed with Barrett's oesophagus with low grade dysplasia, which is pre cancerous cells. I was told the only way to prevent it becoming full blown cancer was to take PPI s for the rest of my life.  Well, 5 years down the track and I'm still on them and now this! 

    Preventing cancer in one pre cancerous organ leads to cancer in another! Go figure!

    RCC

    Renal Cell Carcinoma

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  • medic1971
    medic1971 CSN Member Posts: 225 Member
    #5
    Add me to the list

    I've been on a PPI for about 10 years now and I got RCC.  I know there is a link between PPI and renal function.  I've been trying to ween myself off of the PPI, but it's not easy.  I'm down to 10mg of Prilosec once a day.

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