Question about Side Effects of Chemotherapy (Carboplatin + Taxol)

boda2

Hello!

 

I have been reading threads from here in this site since my Mom was diagnosed both lung adenocarcinoma stage IB and also anal canal cancer stage II. Now she is doing her 4th chemo for lung adenocarcinoma using taxol + carboplatin. Today is about 10 days after the chemo and she is feeling suddenly increased heart rate from time to time, especially when she is lying down. 

 

I wonder if this is a side effect of the chemo medication, e.g. carboplatin or taxol? Thank you for your help!

YL

dennycee

Welcome to the Lung Cancer

Welcome to the Lung Cancer Survivor boards.  If this was my dad I would call the 24 hour line at the oncologists office.  It may simply be a result of the steroids but it should be reported. 

boda2

dennycee said:

Welcome to the Lung Cancer

Welcome to the Lung Cancer Survivor boards.  If this was my dad I would call the 24 hour line at the oncologists office.  It may simply be a result of the steroids but it should be reported. 

Thank you!

Hi Dennycee,

 

Thank you for your suggestion and welcome , I ended up calling the doctor to inform the situation. 

 

Best,

YL

IAmYusufSidi

Answer About the Side-Effects of Chemotherapy For Lung Cancer

Chemotherapy for non-small cell lung tumor

Chemotherapy (chemo) is treatment with hostile to malignancy medications infused into a vein or taken by mouth. These medications enter the circulation system and go all through the body, making this treatment helpful for malignancy anyplace in the body. Contingent upon the phase of non-little cell lung tumor (NSCLC), chemo may be utilized as a part of diverse circumstances:

• Before surgery (once in a while alongside radiation treatment) to attempt to psychologist a tumor. This is known as neoadjuvant treatment.
• After surgery (once in a while alongside radiation treatment) to attempt to slaughter any tumor cells that may have been abandoned. This is known as adjuvant treatment.
• As the fundamental treatment (once in a while alongside radiation treatment) for more propelled tumors or for a few individuals who aren't sufficiently solid for surgery.

 

Specialists give chemo in cycles, with a time of treatment (more often than not 1 to 3 days) trailed by a rest period to permit the body time to recuperate. Some chemo drugs, however, are given each day. Chemo cycles for the most part last around 3 to 4 weeks. Chemo is regularly not suggested for patients in weakness, but rather propelled age independent from anyone else is not a hindrance to getting chemo.

 

The chemo tranquilizes frequently utilized for NSCLC are:

 

• Cisplatin
• Carboplatin
• Paclitaxel (Taxol®)
• Egg whites bound paclitaxel (seize paclitaxel, Abraxane®)
• Docetaxel (Taxotere®)
• Gemcitabine (Gemzar®)
• Vinorelbine (Navelbine®)
• Irinotecan (Camptosar®)
• Etoposide (VP-16®)
• Vinblastine
• Pemetrexed (Alimta®)

 

Frequently, treatment for NSCLC utilizes a blend of 2 chemo drugs. Studies have demonstrated that including a third chemo medication doesn't include much advantage and is liable to bring about more reactions. Single-medication chemo is once in a while utilized for individuals who won't endure blend chemotherapy well for example, those in poor general wellbeing or who are elderly.

On the off chance that a mix is utilized, it frequently incorporates cisplatin or carboplatin in addition to one other medication. Now and again mixes that do exclude these medications, for example, gemcitabine with vinorelbine or paclitaxel, may be utilized.

For individuals with cutting edge lung growths who meet certain criteria, a focused on treatment medication, for example, bevacizumab (Avastin®) or cetuximab (Erbitux®) may be added to treatment also (see "Focused on treatments for non-little cell lung malignancy").

For cutting edge tumors, the introductory chemo blend is regularly given for 4 to 6 cycles. A few specialists now suggest giving treatment past this with a solitary chemo or focused on medication, even in individuals who have had a decent reaction to their starting chemotherapy. A few studies have observed that this proceeding with treatment, known as support treatment, may help hold the growth under wraps and assist some with peopling live more. For more data, see "What's new in non-little cell lung growth exploration and treatment?"

In the event that the beginning chemo treatment for cutting edge lung growth is no more living up to expectations, the specialist may suggest second-line treatment with a solitary medication, for example, docetaxel or pemetrexed. Once more, propelled age is no obstruction to getting these medications the length of the individual is in great general wellbeing.

Conceivable reactions

Chemo medications assault cells that are isolating rapidly, which is the reason they conflict with malignancy cells. Be that as it may, different cells in the body, for example, those in the bone marrow (where fresh recruit cells are made), the mouth's covering and insides, and the hair follicles, additionally separate rapidly. These cells are additionally prone to be influenced by chemo, which can prompt certain symptoms.

 

The reactions of chemo rely on upon the sort and measurements of medications given and the period of time they are taken. Some normal symptoms include:

 

1. Balding
2. Mouth wounds
3. Loss of craving
4. Sickness and spewing
5. Loose bowels or obstruction
6. Expanded possibility of diseases (from having excessively few white platelets)
7. Simple wounding or seeping (from having excessively few blood platelets)
8. Weariness (from having excessively couple of red platelets)

 

These symptoms are typically transient and go away after treatment is done. There are regularly approaches to decrease these symptoms. For instance, medications can be given to help forestall or diminish queasiness and heaving.

 

A few medications can have particular reactions. For instance, medications, for example, cisplatin, vinorelbine, docetaxel, or paclitaxel can bring about nerve harm (fringe neuropathy). This can once in a while lead to side effects (for the most part in the hands and feet, for example, agony, blazing or shivering sensations, affectability to icy or warmth, or shortcoming. In the vast majority this goes away or shows signs of improvement once treatment is halted, yet it might be enduring in a few individuals. For more data, see our archive Peripheral Neuropathy Caused by Chemotherapy.

 

 

You ought to report any reactions you see while getting chemotherapy to your therapeutic group with the goal that they can be dealt with speedily. At times, maybe the dosages of the chemo medications ought to be diminished or treatment may should be deferred or ceased to keep the impacts from getting worse.