Nexavar (Sorafenib) for RAF mutation please help

javier_garcia123

I need to know how good is Nexavar (Sorafenib) at targeting RAF1 mutation, I ask this because Mom used Foundation One, have this mutation, and one of three Targeted Therapies recommended is Sorafenib, the other two being Regorafenib and Trametinib

 

 

The mutation is related to cell division pathway called the MAPK path: MAPK>RAS>RAF>MEK>CCNE1

 

 

 

Also, how to avoid as much as we can nausea? and if you can tell the most frequent side effects in practise and ways to avoid them

Lovekitties

This drug

This drug is not listed as being for colon or rectal cancer.

Here is the web page for this drug from the manufacturer.

http://www.nexavar-us.com/?ecid=NexUS:ps:de:psl:psl:42115:100057

It lists the possible issues and side effects which can present with its use.

 

Marie who loves kitties