surgical pathology report

faithinlord

What is tumor grading regression on surgical pathology report and it's significance related to prognosis of esophageal cancer.

paul61

It is a pathology based treatment response assesment

Tumor grading regression, in a simplistic form, is an analysis of the tumor after chemotherapy to determine the amount of change in the tumor between when the treatment began and when treatment ended. It analyses the reduction in inflammation, the amount of fibrosis, and the reduction in bulk of the tumor. I short it is an approach to gage the patient’s response to the treatment. Here is a reference to a description of the approach:

 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791673/

 Best Regards,

Paul Adams

McCormick, South Carolina

DX 10/2009 T2N1M0  Stage IIB - Ivor Lewis Surgery  12/3/2009 - Post Surgery Chemotherapy 2/2009 – 6/2009

 

Cisplatin, Epirubicin, 5 FU - Four Year Survivor

faithinlord

paul61 said:

It is a pathology based treatment response assesment

Tumor grading regression, in a simplistic form, is an analysis of the tumor after chemotherapy to determine the amount of change in the tumor between when the treatment began and when treatment ended. It analyses the reduction in inflammation, the amount of fibrosis, and the reduction in bulk of the tumor. I short it is an approach to gage the patient’s response to the treatment. Here is a reference to a description of the approach:

 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791673/

 Best Regards,

Paul Adams

McCormick, South Carolina

DX 10/2009 T2N1M0  Stage IIB - Ivor Lewis Surgery  12/3/2009 - Post Surgery Chemotherapy 2/2009 – 6/2009

 

Cisplatin, Epirubicin, 5 FU - Four Year Survivor

post surgery

Hello! Paul

Thank you for your response. Husband had surgery last week. He did fairly ok. As you know lots of pain. He is taking hicet and ibuprofen for that to control. Hicet makes him lit oozy and he was wondering if he will have to take this narcotic for long time. 2nd question is when he lies on his side he gets regurgitation. He is on tube feed.

Could you please give me guideline for how long is he looking Into using hicet narcotic. And regurgitation on lying on side is it a common kind of thing he is experiencing.  I communicated with you in the past and ordered an adjustable bed which is expected to come next week.

Thanks for your input

paul61

faithinlord said:

post surgery

Hello! Paul

Thank you for your response. Husband had surgery last week. He did fairly ok. As you know lots of pain. He is taking hicet and ibuprofen for that to control. Hicet makes him lit oozy and he was wondering if he will have to take this narcotic for long time. 2nd question is when he lies on his side he gets regurgitation. He is on tube feed.

Could you please give me guideline for how long is he looking Into using hicet narcotic. And regurgitation on lying on side is it a common kind of thing he is experiencing.  I communicated with you in the past and ordered an adjustable bed which is expected to come next week.

Thanks for your input

In was taking oxycodone for about two weeks after my surgery

I took Oxycodone for pain for about the first two weeks after my surgery. Like your husband, I did not like the grogginess, fatigue, and constipation that were side effects of the medication. I think the second week I started to reduce my dosage so that I was only taking it at night so I could sleep. After the second week I switched to Tylenol alone and I took that for about another two weeks.

Of course I still had discomfort from the locations where the incisions were made and where the chest tubes were placed. I am afraid that lasts for quite some time. It was about a year before the sensitive area on by back where they did the incision stopped hurting.

 It does take time to recover. For the first week after surgery I got tired and out of breath just getting up, shaving, brushing my teeth, and getting dressed. My first month was pretty much in bed and in my recliner for most of the time. I did try to stand and walk a bit more each day but I was surprised at how weak I was after surgery.  

Of course people respond differently to pain so I am not suggesting that your husband’s time frame will be the same as mine. I my case, I traded some discomfort for the ability to eliminate the side effects of the oxycodone. I would assume Hycet  (hydrocodone) has similar side effects to oxycodone so I am sure your husband will be happy to reach a point that he no longer needs it.

Tell him to be patient, things will gradually improve over time but since this surgery is so major recovery time is substantial.

As far as regurgitation when lying on on his side, I found that I must sleep on my back. Any other position results in reflux. 

Best Regards,

Paul Adams

McCormick, South Carolina
DX 10/2009 T2N1M0  Stage IIB - Ivor Lewis Surgery  12/3/2009 - Post Surgery Chemotherapy 2/2009 – 6/2009
Cisplatin, Epirubicin, 5 FU - Four Year Survivor

 

 

JKGulliver

Your pathology report should give the restaging of your husband's EC.  If you do not see it, you should ask your oncologist or call the surgeon directly.