Has anyone heard of this or been treated in this way? HIPEC

kimberly sue 63
kimberly sue 63 Member Posts: 421 Member
in Ovarian Cancer #1

New treatment effectively kills Ovarian cancer




New treatment effectively kills Ovarian cancer




Doctors are trying a new way to treat Ovarian cancer by using chemotherapy that's been heated up to kill cancer cells.

 

 

 

KABC

 

 

Thursday, June 19, 2014

About 22,000 women are diagnosed with Ovarian cancer each year and more than half die from it. The disease is hard to detect early as often there aren't major symptoms.

Doctors are trying a new way to treat the disease by using chemotherapy that's been heated up to kill cancer cells more effectively.

This year, Helen Szablya and her husband are celebrating 20 years of marriage - a milestone they weren't sure they'd both live to see.

Five years ago, tests showed Szablya had stage four cancer - a tumor so big that doctors said they couldn't even see her ovaries.

"The doctor called me in the next day. He said, 'I need you to understand you have got a very serious kind of cancer," Szablya said.

About 80-percent of ovarian cancers are diagnosed very late, said Armando Sardi, a surgical oncologist.

Sardi offered Szablya a new and aggressive treatment called Hyperthermic Intraperitoneal Chemotherapy or HIPEC. First, he removed all traces of her tumor and her spleen, gall bladder, ovaries, uterus, appendix, fallopian tubes and part of her liver.

Then, he put catheters in Szablya's abdomen and delivered heated chemotherapy. The chemotherapy circulates for 90 minutes and reaches about 109 degrees Fahrenheit.

"Heat kills cancer cells, but also enhances the effects of chemotherapy," Sardi said.

Szablya has been cancer-free for five years!

"It saves your life," she said.

Researchers are studying HIPEC as a first line therapy for women with ovarian cancer in a phase two trial and are now enrolling patients. There are no geographic limitations to the study. Interested patients can enroll by contacting (410) 332-9294.


Found at thid web address:  http://abc7.com/health/new-treatment-effectively-kills-ovarian-cancer/125005/

 

Kim

Comments

  • poopergirl14052
    poopergirl14052 Member Posts: 1,183 Member
    #2
    Yes

    was reading about this and sounds very promising .i wonder if it could help me..Val 

  • ovarian_support
    ovarian_support Member Posts: 44
    #3
    poopergirl14052 said:

    Yes

    was reading about this and sounds very promising .i wonder if it could help me..Val 

    Second Line Treatment

    I read an article on second line treatment in recurrent ovarian cancer, I can't remember where but I will try to find the article if you like.

  • lovesanimals
    lovesanimals Member Posts: 1,366 Member
    #4
    ovarian_support said:

    Second Line Treatment

    I read an article on second line treatment in recurrent ovarian cancer, I can't remember where but I will try to find the article if you like.

    I had not heard of this

    I agree - it sounds promising.

    Kelly

  • kimberly sue 63
    kimberly sue 63 Member Posts: 421 Member
    #5
    poopergirl14052 said:

    Yes

    was reading about this and sounds very promising .i wonder if it could help me..Val 

    ON my inspire board, a doctor

    ON my inspire board, a doctor replied and states this usually done in surgery. I'm not sure what the criteria is to qualify. It is usually only provided at university hospitals in the academia setting. Kim.

  • ovarian_support
    ovarian_support Member Posts: 44
    #6
    Article

    This is the article I read:  http://www.hipectreatment.com/cancers-treated/ovarian-cancer/

    The role of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in the management of recurrent advanced ovarian cancer: a prospective study.



    Abstract

    PURPOSE:

    Ovarian cancer is the leading cause of death from gynecological cancer. The current treatment of this type of cancer consists of cytoreductive surgery (CRS) and systemic chemotherapy. The aim of this study was to examine if the hyperthermic intraoperative chemotherapy (HIPEC) is an alternative modality to treat this category of patients along with asecond attempt of surgical resection and second or third line systemic chemotherapy.

    METHODS:

    Forty-eight patients suffering from advanced ovarian cancer (FIGO stages III and IV) who recurred after initial treatment with conservative or debulking surgery and systemic chemotherapy were included in this study. Twenty-four patients (group A) were treated with CRS followed by HIPEC and then systemic chemotherapy. Due to various reasons the remaining 24 patients (group B) were treated with CRS and systemic chemotherapy alone.

    RESULTS:

    The median survival for group A was 19.4 months vs. 11.2 months in group B (p <0.05). One-year survival was 85% in group A vs. 35% in group B (p <0.05). The 3-year survival rate was 50% in group A vs. 18%. in group B (p <0.01). The resection status was found to be a significant predictor of overall survival (p <0.05). Patients with peritoneal cancer index (PCI) score < 15 appeared also to have longer survival.

    CONCLUSION:

    The use of HIPEC along with the extent of the disease and the extent of cytoreduction play an important role in the survival of patients with a recurrence in an initially advanced ovarian cancer.




    PMID:
     
    21674853
     
    [PubMed - indexed for MEDLINE]

  • abrub
    abrub Member Posts: 2,174 Member
    #7
    HIPEC has been around for a

    HIPEC has been around for a long time as one of the treatments for Appendix Cancer; it is not new.  However, doctors want to get more use out of their HIPEC machines and are looking for other uses, other than colo-rectal cancers.

    I did not have HIPEC for my appendix cancer, but I did have IntraPeritoneal Chemo - 5 3-day cycles.  My hospital didn't do HIPEC at that time, but also felt that IP was comparable in outcome.  They (MSKCC) are now involved in a research protocol comparing HIPEC to IP chemo for Appendix/colorectal cancers.

    Because different chemo drugs are used for Ovarian cancer than that for Appendix/Colorectal cancers, the comparisons between the two modalities might have different results from one type of cancer to another.

    Alice

  • kikz
    kikz Member Posts: 1,345 Member
    #8
    I am

    pretty sure I had this during my surgery.  I should know for sure but the old brain has gotten quite foggy.  I'm going to ask my surgeon when I see him although it won't be until November and I'll probably forget by then.

    Karen

  • MrCLINY
    MrCLINY Member Posts: 10
    #9
    It was advised for my wife

    It was advised for my wife but do to many reasons we were not comfortable about it. It's very expensive for one, two the recovery time can be as much as six months, some insurance companies will not pay for it as it is concided experimental, and there is less than a 40% cure rate. The wife did have a second debunking and is on a third chemo regiment. Her Surgeon had done many HEPIC procedures for the stomach before and did not feel it would be better. So do some reading on the internet about it.

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