Encouraging news on HVP related cancers

PJ47

Probably most of you have heard the news about the clinical trial using targeted T-cell therapy on a young woman with advanced HPV caused cervical cancer that had spread throughout and was threatening to cut off her windpipe.  She and one other person out of 9 had a positive response and is in remission now and one other had a reduction in the tumors!  Yea.  The immunotherapy using one's own T-cells appears to have promise and is being tested on head and neck HPV persons.  I have not had time to look up where but Christian Hinrichs at NCI is involved if you want to look it up.  

PJ

katenorwood

Thanks PJ !

I've been reading quite a few articles on HPV + and - driven cancers.  This one sounds promising.  Katie

hwt

katenorwood said:

Thanks PJ !

I've been reading quite a few articles on HPV + and - driven cancers.  This one sounds promising.  Katie

yes

Saw it on t.v. last night. 2 out of 9 is certainly an indication of a step in the right direction.

PJ47

hwt said:

yes

Saw it on t.v. last night. 2 out of 9 is certainly an indication of a step in the right direction.

Yes it does sound promising

Although it was only 2 out of 9, their cancer was quite advanced and not responding to traditional tx. methods.  They are trying to figure out why two responded and the other 6 (one had some reduction in tumors so I did not count that one) did not respond.  

I like the idea of using your own T-cells to eradicate the cancer.  I suspect the side effects are minimal.  I also wonder about the ages of the two who had good success.  I know one was in her mid 30's.  I am thinking that as we age we most likely do not make T-cells quickly or in the necessary quantity.  So perhaps this will be a good way to increase our T-cells in the future.

I am very happy for the young mother who started with cervical cancer HPV+ and hope this type of research continues asap. 

PJ