PARP drug
I know many of our sisters are on PARP trials . This is fantastic news on the phase 2 PARP BMN 673 for breast cancer. Yes, breast, but read on. I was told that the OVCA results were expected to be released shortly and are as good or better. It seems the BMN 673 had a 50% response rate with numerous "complete" responses. The results were so awesome that they are going straight to phase 3 -- like NOW -- for breast and ovarian, and once phase 3 is out, FDA is expected to fast track it. Could be available by prescription by January!
Here is the link: http://www.benzinga.com/news/13/07/3784909/biomarin-provides-bmn-673-progra m-uupdated
I found this info on another site and wanted to pass along to everyone.
Comments
-
Thank you for posting Shawnna
I believe that PARP inhibitors are the future of OVCA treatment, with more targeted approach and gentler on the body than conventional chemo. FDA approval can't come soon enough!
Watch 42 min long video "Prospects for Targeted Therapy in Ovarian Cancer" presented by Michael Birrer, MD, PhD
He talks about PARP inhibitors from 13:37 till 22:30 min. Bring popcorn.
0 -
Great information. Hopefully
Great information. Hopefully I won't need it since I am celebrating my big 2 months of remission (got to celebrate what you can!!!) But I file this kind of information away "just in case." Thanks so much to both of you for sharing the knowledge that might help us all.
0 -
PARP drug available in January?
Thanks for your post. I am trying to get access to the drug and am interested in knowing if you have any further information about when the drug may be available and whether there are any ovarian trials planned.
Thanks so much for sharing! i am trying to get access to the drug on a compassionate or emergency use basis.
0 -
I have doubts about January...AndreaLivesHere said:PARP drug available in January?
Thanks for your post. I am trying to get access to the drug and am interested in knowing if you have any further information about when the drug may be available and whether there are any ovarian trials planned.
Thanks so much for sharing! i am trying to get access to the drug on a compassionate or emergency use basis.
Hello Andrea,
Go to clinicaltrials.gov, search by drug name and you will see current trials, eligibility requirements and contact information to enroll.
Examples (there are more):
NCT01286987 Study of BMN 673, a PARP Inhibitor, in Patients With Advanced or Recurrent Solid TumorsNCT01844986 Olaparib Monotherapy in Patients With BRCA Mutated Ovarian Cancer Following First Line Platinum Based ChemotherapyNCT01237067 Olaparib in Combination With Carboplatin for Refractory or Recurrent Women's CancersNCT01445418 AZD2281 Plus Carboplatin to Treat Breast and Ovarian CancerNCT01847274 A Maintenance Study With Niraparib Versus Placebo in Patients With Platinum Sensitive Ovarian CancerNCT01690598 Veliparib and Topotecan for Relapsed Ovarian Cancer With Negative or Unknown BRCA Status0
Discussion Boards
- All Discussion Boards
- 6 CSN Information
- 6 Welcome to CSN
- 121.9K Cancer specific
- 2.8K Anal Cancer
- 446 Bladder Cancer
- 309 Bone Cancers
- 1.6K Brain Cancer
- 28.5K Breast Cancer
- 398 Childhood Cancers
- 27.9K Colorectal Cancer
- 4.6K Esophageal Cancer
- 1.2K Gynecological Cancers (other than ovarian and uterine)
- 13K Head and Neck Cancer
- 6.4K Kidney Cancer
- 671 Leukemia
- 793 Liver Cancer
- 4.1K Lung Cancer
- 5.1K Lymphoma (Hodgkin and Non-Hodgkin)
- 237 Multiple Myeloma
- 7.1K Ovarian Cancer
- 61 Pancreatic Cancer
- 487 Peritoneal Cancer
- 5.5K Prostate Cancer
- 1.2K Rare and Other Cancers
- 540 Sarcoma
- 731 Skin Cancer
- 653 Stomach Cancer
- 191 Testicular Cancer
- 1.5K Thyroid Cancer
- 5.8K Uterine/Endometrial Cancer
- 6.3K Lifestyle Discussion Boards