Problem with Perjeta

CypressCynthia
CypressCynthia Member Posts: 4,014 Member
in Breast Cancer #1

Had chemo and, just like last time, I sailed through taxotere and herceptin.  We slowed my perjeta infusion time because last round I had sudden nausea and vomiting.

Slowing infusion time did not help at all.  Five minutes in, I turned beet, beet red, felt burning up and started vomiting.  My nurse gave me ativan stat and I slept through the rest of the infusion and woke up ok.

Nurses didn't like it all and are meeting with the onc.  They want me to take benadryl next round and they are asking about solu medrol.  Ok, that is added to dexamethasone and decadron. 

Danny is busy padding the attic to put me in...Lol.  Steroid hype me up just a bit, but my bathroom cabinets have never looked better! Wink

Any suggestion from Perjeta users with infusion reaction?

Comments

  • smalldoggroomer
    smalldoggroomer Member Posts: 1,184
    #2
    I have been taking Perjeta

    I have been taking Perjeta now for a few months. I have always had Benadryl with it along with the decadron and steroid and never had a reaction to it. I do know what its like to have reactions I have had them to other chemo's Taxotere, Carboplatin, Cisplatin, No fun at all. I don't understand why they didn't just give you the Benadryl in the first place? I have heard that some Dr will keep pushing it until you are in the Hospital. I don't like that, I told my Dr if I start to react stop it. There are other things to try. There is no reason to do that it isn't working! I wish you all the best with what ever you decide to do please feel better.

    Take care Darlin Kay,

  • CypressCynthia
    CypressCynthia Member Posts: 4,014 Member
    #3
    smalldoggroomer said:

    I have been taking Perjeta

    I have been taking Perjeta now for a few months. I have always had Benadryl with it along with the decadron and steroid and never had a reaction to it. I do know what its like to have reactions I have had them to other chemo's Taxotere, Carboplatin, Cisplatin, No fun at all. I don't understand why they didn't just give you the Benadryl in the first place? I have heard that some Dr will keep pushing it until you are in the Hospital. I don't like that, I told my Dr if I start to react stop it. There are other things to try. There is no reason to do that it isn't working! I wish you all the best with what ever you decide to do please feel better.

    Take care Darlin Kay,

    Thanks Kay!  What is weird is

    Thanks Kay!  What is weird is I had no trouble at all on loading dose.  I have always gotten steroids.  Second round I had nausea and vomiting right at end of perjeta-well that is just par for the course for me.  But third time, the immediate flushing, nausea and vomiting shook me up!  I meet with the oncologist before next round and he will figure it out.  Nurses were talking about IV benadryl but ativan also helped immediately and I probably won't get both.

    I am weird but benadryl tend to make me awake and nervous.  But, if it is necessary, well I will do anything!!!

    Thank you so much for your prompt response.  I was so hoping that I would here from you :-).

    How are you feeling?  Still praying for you!  Big (((hugs))).

Discussion Boards