Will Cetuximab work if Kras codon 13 is mutated?
I have no idea what a "codon" is and the article is not easy to read but it is rather informative and hopefully helpful for Kras mutants as it seems to suggest use of cetuximab and/or panitumumab
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0055793
"...In summary,our data make sense in light of five recent studies which demonstrated that KRAS codon 13 mutations but not codon 12 mutations conferred benefit from cetuximab therapy in advanced colorectal cancer."
Discussion Boards
- All Discussion Boards
- 6 CSN Information
- 6 Welcome to CSN
- 122.1K Cancer specific
- 2.8K Anal Cancer
- 448 Bladder Cancer
- 309 Bone Cancers
- 1.6K Brain Cancer
- 28.5K Breast Cancer
- 398 Childhood Cancers
- 27.9K Colorectal Cancer
- 4.6K Esophageal Cancer
- 1.2K Gynecological Cancers (other than ovarian and uterine)
- 13K Head and Neck Cancer
- 6.4K Kidney Cancer
- 673 Leukemia
- 795 Liver Cancer
- 4.1K Lung Cancer
- 5.1K Lymphoma (Hodgkin and Non-Hodgkin)
- 239 Multiple Myeloma
- 7.2K Ovarian Cancer
- 65 Pancreatic Cancer
- 490 Peritoneal Cancer
- 5.5K Prostate Cancer
- 1.2K Rare and Other Cancers
- 543 Sarcoma
- 738 Skin Cancer
- 658 Stomach Cancer
- 192 Testicular Cancer
- 1.5K Thyroid Cancer
- 5.9K Uterine/Endometrial Cancer
- 6.3K Lifestyle Discussion Boards