BMS936558* Votrient trial (formerly MDX 1106) John's 18 week scan

KJones1969

alice124 said:

24 Week Scan
Hi all,

Wish I had better news to report but I'm not complaining. John had his scan today and it showed stabilization, basically no additional shrinkage, but, more importantly, no growth.

While he was awaiting his scan, his research nurse (the dear Monica) talked to him about Afinitor as a possible next step if his scan showed growth, but since it's stable, he will remain in trial. Next scan will be in 12 weeks. Will keep our fingers crossed for continued stabilization.

____________________________________

John’s History at Johns Hopkins:

10/14/11 – Diagnosed with Kidney cancer clear cell/grade 4/stage 4 – with sarcomatoid features and lung mets; also has soft tissue mass in shoulder area and pelvic area.

Symptoms: weight loss followed by cough
11/1/11 – Surgery for removal of right kidney (nephrectomy)

Treatments to date:
January & February 2012 -HDIL2 treatment/first round 14 doses/2nd round 10 doses;
(discontinued after February 2012 as scan did not merit continuation)

5/10/2012 – Began MDX1106/Votrient trial BMS 936558
6/20/2012–CT scan showed 31% reduction in tumor burden;
8/1/2012–CT scan showed add'l 11% tumor reduction for total of 42%:
9/12/2012 – CT scan showed 46% reduction in tumor burden (4% addl.
10/24/2012 - CT scan reflected stabiliztion

At least no new growth
Alice,

No new growth is good but I know how you feel. My husband's 3 month scan was great, then 10 weeks later and his shrinkage had enlarged with new spots. My husband started Afinitor and I am very interested in knowing how he does with that. I will keep you and John in my prayers and will let you know how my husband does with Afinitor.

Karen

KJones1969

alice124 said:

24 Week Scan
Hi all,

Wish I had better news to report but I'm not complaining. John had his scan today and it showed stabilization, basically no additional shrinkage, but, more importantly, no growth.

While he was awaiting his scan, his research nurse (the dear Monica) talked to him about Afinitor as a possible next step if his scan showed growth, but since it's stable, he will remain in trial. Next scan will be in 12 weeks. Will keep our fingers crossed for continued stabilization.

____________________________________

John’s History at Johns Hopkins:

10/14/11 – Diagnosed with Kidney cancer clear cell/grade 4/stage 4 – with sarcomatoid features and lung mets; also has soft tissue mass in shoulder area and pelvic area.

Symptoms: weight loss followed by cough
11/1/11 – Surgery for removal of right kidney (nephrectomy)

Treatments to date:
January & February 2012 -HDIL2 treatment/first round 14 doses/2nd round 10 doses;
(discontinued after February 2012 as scan did not merit continuation)

5/10/2012 – Began MDX1106/Votrient trial BMS 936558
6/20/2012–CT scan showed 31% reduction in tumor burden;
8/1/2012–CT scan showed add'l 11% tumor reduction for total of 42%:
9/12/2012 – CT scan showed 46% reduction in tumor burden (4% addl.
10/24/2012 - CT scan reflected stabiliztion

At least no new growth
Alice,

No new growth is good but I know how you feel. My husband's 3 month scan was great, then 10 weeks later and his shrinkage had enlarged with new spots. My husband started Afinitor and I am very interested in knowing how he does with that. I will keep you and John in my prayers and will let you know how my husband does with Afinitor.

Karen

KJones1969

alice124 said:

24 Week Scan
Hi all,

Wish I had better news to report but I'm not complaining. John had his scan today and it showed stabilization, basically no additional shrinkage, but, more importantly, no growth.

While he was awaiting his scan, his research nurse (the dear Monica) talked to him about Afinitor as a possible next step if his scan showed growth, but since it's stable, he will remain in trial. Next scan will be in 12 weeks. Will keep our fingers crossed for continued stabilization.

____________________________________

John’s History at Johns Hopkins:

10/14/11 – Diagnosed with Kidney cancer clear cell/grade 4/stage 4 – with sarcomatoid features and lung mets; also has soft tissue mass in shoulder area and pelvic area.

Symptoms: weight loss followed by cough
11/1/11 – Surgery for removal of right kidney (nephrectomy)

Treatments to date:
January & February 2012 -HDIL2 treatment/first round 14 doses/2nd round 10 doses;
(discontinued after February 2012 as scan did not merit continuation)

5/10/2012 – Began MDX1106/Votrient trial BMS 936558
6/20/2012–CT scan showed 31% reduction in tumor burden;
8/1/2012–CT scan showed add'l 11% tumor reduction for total of 42%:
9/12/2012 – CT scan showed 46% reduction in tumor burden (4% addl.
10/24/2012 - CT scan reflected stabiliztion

At least no new growth
Alice,

No new growth is good but I know how you feel. My husband's 3 month scan was great, then 10 weeks later and his shrinkage had enlarged with new spots. My husband started Afinitor and I am very interested in knowing how he does with that. I will keep you and John in my prayers and will let you know how my husband does with Afinitor.

Karen

KJones1969

alice124 said:

24 Week Scan
Hi all,

Wish I had better news to report but I'm not complaining. John had his scan today and it showed stabilization, basically no additional shrinkage, but, more importantly, no growth.

While he was awaiting his scan, his research nurse (the dear Monica) talked to him about Afinitor as a possible next step if his scan showed growth, but since it's stable, he will remain in trial. Next scan will be in 12 weeks. Will keep our fingers crossed for continued stabilization.

____________________________________

John’s History at Johns Hopkins:

10/14/11 – Diagnosed with Kidney cancer clear cell/grade 4/stage 4 – with sarcomatoid features and lung mets; also has soft tissue mass in shoulder area and pelvic area.

Symptoms: weight loss followed by cough
11/1/11 – Surgery for removal of right kidney (nephrectomy)

Treatments to date:
January & February 2012 -HDIL2 treatment/first round 14 doses/2nd round 10 doses;
(discontinued after February 2012 as scan did not merit continuation)

5/10/2012 – Began MDX1106/Votrient trial BMS 936558
6/20/2012–CT scan showed 31% reduction in tumor burden;
8/1/2012–CT scan showed add'l 11% tumor reduction for total of 42%:
9/12/2012 – CT scan showed 46% reduction in tumor burden (4% addl.
10/24/2012 - CT scan reflected stabiliztion

At least no new growth
Alice,

No new growth is good but I know how you feel. My husband's 3 month scan was great, then 10 weeks later and his shrinkage had enlarged with new spots. My husband started Afinitor and I am very interested in knowing how he does with that. I will keep you and John in my prayers and will let you know how my husband does with Afinitor.

Karen

Limelife50

alice124 said:

Stable
Thanks Tacyarts - right back to you.

I have to ask -- Stray Cats -- is that named for your wild and unattached friends or the four legged creatures? Since feral/stray cats are a part of my life and volunteerism, just wondering. . .

On one of your appointments, hope to meet you and your wife in person at Hopkins!!! Know you both are in my prayers.

I guess Half full will work
Hi Alice wish you and John could have gotten maybe a little better results but then again stable disease does have a nice ring to it.