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Doxorubicin

Tina Brown
Tina Brown CSN Member Posts: 1,036 Member
edited April 2012 in Ovarian Cancer #1
I know there is currently a shortage of Doxil (USA) Caelyx (UK) so when my oncologist prescribed Caelyx for me last week (How can he not know it had been discontinued - doh) his team managed to substitute it for a different Chemo - Doxorubicin.

I was told that it is similar to Doxil/Caelyx but doesn't have the coating on it that protects the heart and prevents hair loss.

So I was wondering if anyone out there had had this chemo and if so DID IT WORK? Its only been about 8 weeks since I finished Topotecan and I am feeling quite weary and nauseated on this drug.

Any imput will be greatly received. Love Tina xxxx
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Comments

  • jt25741
    jt25741 CSN Member Posts: 23
    #2
    My wife was going to go on Doxorubicin, but the Dr's obtained some other drug called Lipodox. It is the liposomal form of Doxorubicin, just like Doxil is (that pegylated coating you talked about). This not only protects the organs, but also may target the tumor better -- and lasts in the system longer with fewer side-effects. This way treatment schedules can be easier to tolerate. You may want to ask about Lipodox. It has very recently been allowed in the USA as a substitute for Doxil...not sure about the details of availability elsewhere.

    Best wishes

    Jim
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  • Cynthia Rose
    Cynthia Rose CSN Member Posts: 35
    #3
    jt25741 said:

    My wife was going to go on Doxorubicin, but the Dr's obtained some other drug called Lipodox. It is the liposomal form of Doxorubicin, just like Doxil is (that pegylated coating you talked about). This not only protects the organs, but also may target the tumor better -- and lasts in the system longer with fewer side-effects. This way treatment schedules can be easier to tolerate. You may want to ask about Lipodox. It has very recently been allowed in the USA as a substitute for Doxil...not sure about the details of availability elsewhere.

    Best wishes

    Jim

    Good to Know!!!!!!!
    That is GREAT news there is a Substitute for Doxil! My Mom Has Stage 4 Uterine cancer and is Treated like Ovarian She is now on Carbo/Gezmar.
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  • Cynthia Rose
    Cynthia Rose CSN Member Posts: 35
    #4
    jt25741 said:

    My wife was going to go on Doxorubicin, but the Dr's obtained some other drug called Lipodox. It is the liposomal form of Doxorubicin, just like Doxil is (that pegylated coating you talked about). This not only protects the organs, but also may target the tumor better -- and lasts in the system longer with fewer side-effects. This way treatment schedules can be easier to tolerate. You may want to ask about Lipodox. It has very recently been allowed in the USA as a substitute for Doxil...not sure about the details of availability elsewhere.

    Best wishes

    Jim

    Good to Know!!!!!!!
    That is GREAT news there is a Substitute for Doxil! My Mom Has Stage 4 Uterine cancer and is Treated like Ovarian She is now on Carbo/Gezmar.
    Like Care

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