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BRCA1, Grapefruit, and Strontium

Tethys41
Tethys41 CSN Member Posts: 1,383 Member
in Ovarian Cancer #1
As always, I gained a couple of new tidbits of information from my naturopath at my appointment today. Sorry, I cannot quote the sources, as she said these were just small mentions in larger, unrelated papers. BRCA1 positive wormen should NEVER eat grapefruit as it interferes wtih the p450 pathway. And BRCA1 women should not take strontium, as it increases their risk of heart attack and stroke.
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  • carolenk
    carolenk CSN Member Posts: 907 Member
    #2
    Grapefruit interferes with
    Grapefruit interferes with everyone's p450 detox pathway--there must be more to that tidbit of info that makes it more significant for BRACA + women.

    If you do urine analysis, just about everyone has strontium in their tissues. I think we got it from the nuclear testing that was done out West decades ago. Strontium may be found in some supplements that are designed for improving bone strength. Those supplements often have excessive amounts of calcium that end up in arteries instead of bones.

    Thanks for posting.
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  • Tethys41
    Tethys41 CSN Member Posts: 1,383 Member
    #3
    carolenk said:

    Grapefruit interferes with
    Grapefruit interferes with everyone's p450 detox pathway--there must be more to that tidbit of info that makes it more significant for BRACA + women.

    If you do urine analysis, just about everyone has strontium in their tissues. I think we got it from the nuclear testing that was done out West decades ago. Strontium may be found in some supplements that are designed for improving bone strength. Those supplements often have excessive amounts of calcium that end up in arteries instead of bones.

    Thanks for posting.

    p450
    I've had a lot of genetic testing done since my treatment. My p450 pathway does not operate properly, so I can't afford to eat anything that messes with it. I assume this genetic defect must be somehow linked to my BRCA1 mutation.
    Strontium is available in supplement form alone, without calcium or other minerals. I was taking it to try to reduce bone loss, but not anymore. It wasn't working anyway.
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  • whiterose
    whiterose CSN Member Posts: 89
    #4
    Hi Tethys
    Thanks for posting this. I always enjoy reading your nuggets of information. They spur me to do more research. Thanks
    again.

    Sue
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