The Cancer Survivors Network (CSN) is a peer support community for cancer patients, survivors, caregivers, families, and friends! CSN is a safe place to connect with others who share your interests and experiences.
Thank you for being a part of the Cancer Survivor Network community. Survivors and caregivers like you have played a unique role in fostering an online environment that encourages connection among those needing support, community, and education. On May 28, the Network will be discontinued. More details are available here . If you have any questions, contact CSNSupportTeam@cancer.org. Thanks again for the support you’ve provided each other over the years. We remain committed to supporting you in other ways throughout your cancer journey.
Leuprolide's effect on chemotherapy's ability to kill cancer-cells? References to research greatly
ender
CSN Member Posts: 167
Hi everyone!
Today I must decide if I should start taking Luprolide (brand-name Lupron) while I am on my chemo. Does anyone know of research papers in this area? I found a quote on breastcancer.org, http://www.breastcancer.org/tips/fert_preg_adopt/fertility/chemotherapy.jsp, saying that:
"Ovarian function can be temporarily stopped, or suppressed, during chemotherapy by medication. Some believe this may help protect the immature eggs from damage during treatment. But there is a lot of disagreement among experts about this issue. So far there have been no reliable clinical studies on this issue.
Doctors are also concerned that the drugs used in ovarian suppression may interfere with chemotherapy's ability to kill the cancer cells. This is because chemotherapy is most effective against cancer cells when they're actively growing. Hormonal therapy — which is used to suppress the ovaries — can also stop or slow the growth of the breast cancer cells. This may make the cells less sensitive to chemotherapy."
This sounds logical and concerns me. I am unable to find this concern restated elsewhere. Any links or search-tips would be great!
Eva
Today I must decide if I should start taking Luprolide (brand-name Lupron) while I am on my chemo. Does anyone know of research papers in this area? I found a quote on breastcancer.org, http://www.breastcancer.org/tips/fert_preg_adopt/fertility/chemotherapy.jsp, saying that:
"Ovarian function can be temporarily stopped, or suppressed, during chemotherapy by medication. Some believe this may help protect the immature eggs from damage during treatment. But there is a lot of disagreement among experts about this issue. So far there have been no reliable clinical studies on this issue.
Doctors are also concerned that the drugs used in ovarian suppression may interfere with chemotherapy's ability to kill the cancer cells. This is because chemotherapy is most effective against cancer cells when they're actively growing. Hormonal therapy — which is used to suppress the ovaries — can also stop or slow the growth of the breast cancer cells. This may make the cells less sensitive to chemotherapy."
This sounds logical and concerns me. I am unable to find this concern restated elsewhere. Any links or search-tips would be great!
Eva
Discussion Boards
- All Discussion Boards
- 7 Cancer Survivors Network Information
- 6 Welcome to CSN
- 1 CSN Update
- 122.7K Cancer specific
- 2.8K Anal Cancer
- 457 Bladder Cancer
- 311 Bone Cancers
- 1.7K Brain Cancer
- 28.6K Breast Cancer
- 410 Childhood Cancers
- 28K Colorectal Cancer
- 4.6K Esophageal Cancer
- 1.2K Gynecological Cancers (other than ovarian and uterine)
- 13.1K Head and Neck Cancer
- 6.4K Kidney Cancer
- 682 Leukemia
- 805 Liver Cancer
- 4.2K Lung Cancer
- 5.1K Lymphoma (Hodgkin and Non-Hodgkin)
- 243 Multiple Myeloma
- 7.2K Ovarian Cancer
- 71 Pancreatic Cancer
- 493 Peritoneal Cancer
- 5.7K Prostate Cancer
- 1.2K Rare and Other Cancers
- 544 Sarcoma
- 745 Skin Cancer
- 662 Stomach Cancer
- 194 Testicular Cancer
- 1.5K Thyroid Cancer
- 5.9K Uterine/Endometrial Cancer
- 6.5K Lifestyle Discussion Boards