Anyone with confirmed KRAS or Braf mutations:trial starting at UNC-Chapel Hill now (plus another ite

coloCan
coloCan Member Posts: 1,944 Member
edited March 2011 in Colorectal Cancer #1
if you are eligible for second line Tx for mets, tho of 240 people to be selected some it appears will be givena placebo (This I dislike) for something called regorafenib......

see www.healthcanal.com/cancers/15667-UNC-lead-study-new-option-for-some-colon-cancer-patients.html

since above proved sopopuar,I;ll add the following I just saw, tho I can give the site. as don't know link....Pertains also to BRAF--MEK-ERK pathway as well as KRAS, involving AZD6244, a new drug, titled: "Babraham researchers discover how tumor cells acquire resistence to new emerging drugs" at today's, 3/29/11

insciences.org

Comments

  • lisa42
    lisa42 Member Posts: 3,625 Member
    #2
    Thanks
    I actually did read about this trial, but I will not ever do a trial that has the possibility of me taking a placebo. I just can't risk that. I guess if I got that desperate, I'd rather do something else. But, it is interesting to see that there are trials for KRAS mutants, like myself. I know of a couple of others too that are for us "mutants".

    Thanks for the info-
    Lisa
  • coloCan
    coloCan Member Posts: 1,944 Member
    #3
    lisa42 said:

    Thanks
    I actually did read about this trial, but I will not ever do a trial that has the possibility of me taking a placebo. I just can't risk that. I guess if I got that desperate, I'd rather do something else. But, it is interesting to see that there are trials for KRAS mutants, like myself. I know of a couple of others too that are for us "mutants".

    Thanks for the info-
    Lisa

    Me neither,Lisa...i want something real, not my imagination....
    The "placebo effect", (sorta if you think its happenin it is)I feel is too risky to try with cancer, at least for me....If mind over reality worked for us, we'd all wish our cancer away...but along with attitude or positive thoughts,we need something a little stronger to assist us, like a couple of more powerful,cancer -eradicating with minimal, or no bad side effects-solutions.

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