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Anyone Taxol resistant? This might be of interest....

Hissy_Fitz
CSN Member Posts: 1,834 Member
The UK's Telegraph (8/17, Adams) reported, "At present the chemotherapy drug
paclitaxel, also known by its brand names Paxol and Abraxane, is often
prescribed to shrink ovarian tumors by stopping cancer cells dividing," but
"some ovarian cancers are resistant to such drugs, known as taxanes." Now,
researchers "believe they have opened up a new route after identifying a key
protein." According to the paper in Cancer Cell, the investigators discovered
"that cells struggled to divide when they interfered with a gene known as SIK2,
which produces the protein," and "by blocking the protein, they found that
ovarian cancer cells became more sensitive to paclitaxel."
paclitaxel, also known by its brand names Paxol and Abraxane, is often
prescribed to shrink ovarian tumors by stopping cancer cells dividing," but
"some ovarian cancers are resistant to such drugs, known as taxanes." Now,
researchers "believe they have opened up a new route after identifying a key
protein." According to the paper in Cancer Cell, the investigators discovered
"that cells struggled to divide when they interfered with a gene known as SIK2,
which produces the protein," and "by blocking the protein, they found that
ovarian cancer cells became more sensitive to paclitaxel."
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