My mom was diagnosed on may 5th, 2010 with B cell Non-hogdkins lymphoma NOS with splenic involvement. About a week later, her spleen was removed and was the size of a nerf football. They doctor said that was around 90% of the cancer. So last friday, she went in for her first R-CHOP chemo treatment. It lasted about 8 hours. After getting home, she was tired from sitting still all day. Saturday she rested all day. Sunday she kind of got up and around, we thought gradually improving and that would be the end of it. Then monday and tuesday she returned to work. Wednesday and today have been awful. Nausea and aches and pains all day and night to go with the sleeplessness. Her ankle has been hurting quite a bit. We think she may be dehydrated, so tomorrow morning she's going in for a checkup with her onc and we're gonna see if they'll give her some fluids there. But I was wondering how normal is this nausea with r-chop? I mean, we've been through three different nausea meds now, and none have worked. Prometh, ativan, and I'm not sure of the other but there is seemingly no improvement whatsoever. I'm not sure if anyone out there has been through this or not.. When she was first diagnosed it was stage 3. But after tests revealsed it WASN'T in here bone marrow or spine, he moved it to stage 2. 100% curable is what we're told. I'm seeing these awful stories of getting rituxan over and over for months and months after chemo is done, and if that's what's making her so sick, I don't want that.. Thanks!