Question about K-RAS

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jmaddox915
jmaddox915 Member Posts: 80 Member
edited March 2014 in Colorectal Cancer #1
Can someone tell me exactly what the K-RAS is? I just read through some of my medical records and it says I am negative for this. Is that good or bad?

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  • zenmonk
    zenmonk Member Posts: 198
    #2
    kras
    Its alot more involved than this but basically when your kras are mutated it means that the cetuximab drug is ineffective. So I think this is good for you as it gives you another option in treatment.
  • Paula G.
    Paula G. Member Posts: 596
    #3
    Yes
    I don't know everything about the gene but if you have a mutant gene you will not respond to the drug Cetuximab ( Erbitux) If you are negative or I have heard wild used also you can take this drug and it should be effictive. There is a guy on here his name is Phil that had good results with this drug. So it is a good thing you have another option if the other drugs aren't working. Good luck Paula
  • lisa42
    lisa42 CSN Member Posts: 3,625 Member
    #4
    good
    If you're negative for the kras mutation, that means you're kras wild type. Erbitux and Vectibux are the drugs affected by kras. If you're negative for kras, then these drugs can be used for you. If you had the kras mutation (as I do), then these drugs would be ineffective for your treatment.

    Lisa
  • Paula G.
    Paula G. Member Posts: 596
    #5
    lisa42 said:

    good
    If you're negative for the kras mutation, that means you're kras wild type. Erbitux and Vectibux are the drugs affected by kras. If you're negative for kras, then these drugs can be used for you. If you had the kras mutation (as I do), then these drugs would be ineffective for your treatment.

    Lisa

    Thanks
    Thanks Lisa,
    I knew someone would know more I actually hadn't heard of Vectibux mantioned before. I must be in the same class huh?
  • jmaddox915
    jmaddox915 Member Posts: 80 Member
    #6
    Paula G. said:

    Thanks
    Thanks Lisa,
    I knew someone would know more I actually hadn't heard of Vectibux mantioned before. I must be in the same class huh?

    Thank you all for your
    Thank you all for your response. So far I am responding well to the Folfox treatment with Avastin. I have two more treatments left and I am praying hard for a clean scan.

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