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real-world better than clinical trials

taraHK
taraHK CSN Member Posts: 1,952 Member
edited March 2014 in Colorectal Cancer #1
I just watched a video interview clip from Medscape.com (free but I think you're supposed to be a medical doctor to sign up -- I lied). It was mainly about Avastin and colorectal cancer. But one of the main points made by the doctor interviewed was: the results which doctors are seeing for advanced colorectal cancer in the "real world" are much better than those reported in clinical trials and published studies in medical journals, etc. Even recent, well-conducted studies.

This is something many of us believe to be true already! But it was nice -- and heartening -- to hear this "expert" say so......(a Dr. John Marshall from Georgetown Univ.....).

http://www.medscape.com/viewarticle/584866?src=mp&spon=17&uac=75526PR

Tara
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Comments

  • msccolon
    msccolon CSN Member Posts: 1,917 Member
    #2
    Physician Assistant here!
    It NEVER occurred to me to just lie on one of those sites to get access to the really good stuff! hehehehehe! Thanks for the info! That was a good video and I think I'm going to surf that site... got to keep on top of my profession, you know!
    mary
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  • msccolon
    msccolon CSN Member Posts: 1,917 Member
    #3
    another interesting article
    on that site! This one discusses whether doctors report prognosis, yada yada http://www.medscape.com/viewarticle/584637
    mary
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  • taraHK
    taraHK CSN Member Posts: 1,952 Member
    #4
    msccolon said:

    another interesting article
    on that site! This one discusses whether doctors report prognosis, yada yada http://www.medscape.com/viewarticle/584637
    mary

    Lying? Or being proactive ?!
    That is a good article, too, Mary.

    Maybe we shouldn't use the term "lie" -- how about "taking an active role in one's health"?? Ha ha.

    It is a good site and I find the articles relevant and written in fairly "lay" terms.....

    Tara
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  • msccolon
    msccolon CSN Member Posts: 1,917 Member
    #5
    taraHK said:

    Lying? Or being proactive ?!
    That is a good article, too, Mary.

    Maybe we shouldn't use the term "lie" -- how about "taking an active role in one's health"?? Ha ha.

    It is a good site and I find the articles relevant and written in fairly "lay" terms.....

    Tara

    hey, whatever gets it done!
    Are they going to come and take our fingers off our keyboards?!!! I agree, they are very easy to read and my onc is going to hate that I found that site next time I corner him with questions!
    mary
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  • msccolon
    msccolon CSN Member Posts: 1,917 Member
    #6
    Pharmacogenetics in Colorectal Cancer: A Systematic Review
    http://www.medscape.com/viewarticle/584383?src=mp&spon=7&uac=
    It's really long, but some interesting information. Discusses gene interactions with drugs like Oxaliplatin, CPT-11, 5-FU, Avastin, etc. No wonder we get such a wide variety of reactions and responses to these drugs. The future is in individualizing our treatments according to various genome characteristics!

    http://www.medscape.com/viewarticle/584891?src=mp&spon=7&uac=
    This one discusses the use of Xeloda and CPT-11 as a first-line therapy for metastatic CRC. The printed version has some really cool charts too! :)
    mary
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