Is there anyone out there who had neoadjuvent (before surgery) therapy for Her-2 positive breast cancer. I am about 2 1/2 years post surgery, invasive ductal carcinoma 6.5 cm, possible positve early lymph node involvement on PET scan but negative at time of surgery 6 months later. Chemo of taxotere and carboplatin and herceptin before surgery and a few treatments with herceptin after surgery before MUGA scan stopped the treatments. Doctor says it is a "miracle drug" nothing to worry about in the future. I can be paronoid and not sure I believe in miracles. Never anything in the news except how wonderful Herceptin is. Is it possible that there really are not any negatives? Never had any type of follow-up scans other than the mammograms since they are "no longer recommended". Probably no need to add that I can get pretty depressed. Anyone else with a similar story?