Folfox6 Side Effects?

kbienapfl Member Posts: 61
edited March 2014 in Colorectal Cancer #1
Hi Gang. Knowing that a number of you have 'been there and done that', I am hoping you can answer a couple of post chemo questions for me.

I just completed my third round of Folfox6 with Erbitux this past Monday, with my 5-FU pump removed Wednesday. I am feeling pretty well today with the exception of two concerns. I have a chronic dry cough as well as pain in what appears to be in my liver area. The liver pain is of greater concern. It feels like I have been kicked in the area repeatedly. I woke in the night very uncomfortable and quite frankly, scared.

Is this normal post chemo side effects? Does the liver over dose on these chemicals and can't keep up? Just wondering if any of you have had these same post symptoms.

Thank you in advance. You are all great.


  • NWmom
    NWmom Member Posts: 80
    Hi k,
    My husband had a chronic cough with his FOLFOX and Avastin treatment. His onc couldn't explain it, but he only had it after treatment for a week or so, then it would vanish till his next treatment. Now that he is done with treatment, he hasn't had any more cough issues.
    Unfortunately, I have no idea about your liver pain- definitely talk to your doc!
    Good luck,
    Heather and Carl
  • Faith4Cure
    Faith4Cure Member Posts: 405 Member
    My husband got very hoarse with a dry throat after his Folfox. I'm not sure about your liver pain. I do know that my husband's liver enzymes went up to very high levels while he was on the chemo. He was also on Lipitor for cholesterol at the time. After he quit taking the Lipitor his levels went back to normal. I am sure that the chemo has some effect on the liver---just not sure about the pain. Be sure to tell your doctor, but for right now, try not to get too worried. Keep us posted!

  • apache4
    apache4 Member Posts: 272 Member
    My first couple of treatments with 5-fu, etc. caused pain in my liver. The nurse said that it "irritated" the liver. It almost felt like it had a life of it's own and was kicking me. It was not so painful as scary. It stopped around the fourth treatment. It still does that occasionally now, two months after my last chemo, and I can't figure out why and either does my onc know. I just try not to panic as that makes it worse.
  • kerry
    kerry Member Posts: 1,313 Member
    I've been on all the chemo you are taking with the exception of Erbutux. I have had a chronic dry cough, nose bleeds, scratchy throat, chest pains, as well as pains in the area of the liver. I also had radiation in my abdominal area and have recently experienced pain where the radiation was.

    I would say all of the above are pretty normal post chemo side effects. Some of us experience more than others, some experience hardly any. I've been on chemo for almost 5 years and I guess I've experienced about all of them.

    Just make sure you tell the doctor - and don't let him poo-poo it. Make sure it concerns him and he checks on it or gives you an answer.

    My best to you.

  • kbienapfl
    kbienapfl Member Posts: 61
    Thank you for taking the time to respond. I am feeling better today. The symptoms must be the way my body processes. My liver doesn't feel like it has been kicked and punched this morning, although the chemo must do a number to it!

    Today will be a day of renewed energy. I am rested and ready to face the world with a smile.

    Your support is amazing. You are appreciated.

  • kbienapfl
    kbienapfl Member Posts: 61
    I have been prescribed azithromycin (Z-pack) for my cough. I went in for my Erbitux treatment this morning and they became concerned. Nothing to fool with when ones white blood count is tanked.

    Once again, I am on a series of five Neuopgen injections. My bone marrow just does not want to create the white blood cells needed to defend me!

    I realize now the pain in the liver area was my body processing the toxins that it had received earlier in the week. For future reference, my acupuncturist suggests a heating pad next time to help alleviate the discomfort.