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Change in chemo

Monicaemilia
Monicaemilia CSN Member Posts: 455 Member
edited March 2014 in Colorectal Cancer #1
I was dx in Jan. 05, and did 11 cycles of Oxaliplatin, Xeloda which kept everything stable. In December, we switched to 5FU, Irinotecan, Leucovorin and Avastin. I have a c-scan coming up on January 23 and, I have to admit, there is a part of me that doesn't even want to show to the scan (ignorance can be such heavenly bliss). Of course, I will go, but here's my question: Has anyone switched from Oxaliplatin or Folfox to Folfiri and what were the results? Monica
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  • joyceann619
    joyceann619 CSN Member Posts: 33 Member
    #2
    Hi Monica,
    Yes, my first treatment was Folfox then I had a 6 month break, my CEA increased and my Catscan showed more growth so I went on Folfiri. First of all, do you know why are they changing your chemo?

    I had less side effects with Folfiri, especially no cold sensitivity but I was more tired .

    As far as keeping the cancer stable, the Folfox kept it stable longer than the Folfiri. But that's me and everyone responds differently.

    Joyce
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  • vinny3
    vinny3 CSN Member Posts: 928 Member
    #3
    I didn't have a change but stopped the Folfox after 9 cycles. I guess the most important question is why the chemo was changed before the CT scan.

    ****
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  • Monicaemilia
    Monicaemilia CSN Member Posts: 455 Member
    #4
    vinny3 said:

    I didn't have a change but stopped the Folfox after 9 cycles. I guess the most important question is why the chemo was changed before the CT scan.

    ****

    Joyce and Vinny: Thanks for the response. The reason they are changing the regimen is because we are working towards shrinkage so that surgery can take place. One of the tumours in the liver is too close to a vein and it would be risky to attempt surgery. Although stability is good, in my case it is not because it impedes the possibility of surgery.
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  • Monicaemilia
    Monicaemilia CSN Member Posts: 455 Member
    #5
    Monicaemilia said:

    Joyce and Vinny: Thanks for the response. The reason they are changing the regimen is because we are working towards shrinkage so that surgery can take place. One of the tumours in the liver is too close to a vein and it would be risky to attempt surgery. Although stability is good, in my case it is not because it impedes the possibility of surgery.

    Sorry ****, your dog keeps confusing me.
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