We have just completed round two of DBVE. We have been giving Jared his daily injections of GCSF to maintain his blood levels. Well, they never did drop, and as a matter of fact, they are so high, too high now. The hospital has told us to stop giving him the G shots because now he is experiencing back pain. This is my question.......Has anyone ever experienced something like this? I am worried that maybe he is not responding to the chemo. Or, maybe the G is doing it's job, but how do they tell if the chemo is working when all of his levels are so high. I am so confused!!! I guess I should feel lucky that he has never been neutropenic or got any infections, but something in my head is telling me different. His total ANC today is 27,000. His White cells are 31, and his platelets are 289,000. I would appreciate any advice or experiences with this. Thank you all.