Anyone with progressive liver mets...
Comments
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Glow,
I'm sorry to hear that the mets are progressing...but without meds I guess that's what happens. I have mets to lungs and liver and have been doing a clinical trial of avastin and taxol. My lungs have been in remission since June and my liver tumors are now stable...no more shrinkage on last ct. Stable is good. You should ask your doctor about avastin...I'm hearing that it may be approved soon for bc (already approved for colon cancer). It is one of the veg drugs that chokes the blood supply to the tumor. I don't blame you for not wanting to go back on chemo...that's a decision you have to make for yourself.
I have just started cycle 11, chemo #31 this week...there are side effects but is doable. I feel fortunate that I am tolerating treatment as well as I am. I might not be as lucky with the next tx. Are you er/pr positive...then you could try the hormonals. Best of luck to you and keep us posted
Warmly,
Judiek
History
Discovered lump Sept. 2002 (mammo didnt pick it up)
Dx Oct 2002-just turned 41
IDC and pagets disease, stage 2B, grade 3/3, nottingham scale 9/9
3cm, lumpectomy,clean margins
er/pr-pos, her2 neg, 2/25 nodes w/cancer
Nov 2002-March 2003-FEC (5fu, epirubicin, cytoxen)
March 2003- started tamoxifen
May 2003- finished rads (33tx)
June 2003-CT/PET Scan- clear
Started 3 month check ups w/lab
Dec 2003-complete hysterectomy
Jan 2004-extensive mets, both lungs & liver(labs normal)
Jan -stopped tamoxifen
Feb CEA-23 (0-3 normal) CA27.29-66.1 (0-38 normal)
Feb 23to current-clinical trial, taxol & avastin
April 15th, -CT-significant shrinkage on all tumors/plueral effusion gone
June 8th -CT-all liver lesions decreased in size/lung mets gone
Aug 9th, -CA27.29 is 22.3, CEA is .8)
Aug 9th, 2004-Brain-CT neg, lung mets/pleural effusion still gone, liver mets had slight shrinkage. Largest hypodesne lesion is 2.1cm, 6 others 1cm or less.
Sept 13th-bone scan negative, mri revealed herniated disc.
Sept 27- Ct of brain, negative/lung mets still gone/ 2 liver lesions gone, 4 under 1cm, 1 @1.7cm.
Nov 29-CA27.29 is 24, CEA is 2.4
Nov 29-CT shows stable, lungs still clear, liver tumors stable0 -
Thanks for you reply. Have been on all hormones except Fasladex. I will ask about avista. Thanks so much.judiek said:Glow,
I'm sorry to hear that the mets are progressing...but without meds I guess that's what happens. I have mets to lungs and liver and have been doing a clinical trial of avastin and taxol. My lungs have been in remission since June and my liver tumors are now stable...no more shrinkage on last ct. Stable is good. You should ask your doctor about avastin...I'm hearing that it may be approved soon for bc (already approved for colon cancer). It is one of the veg drugs that chokes the blood supply to the tumor. I don't blame you for not wanting to go back on chemo...that's a decision you have to make for yourself.
I have just started cycle 11, chemo #31 this week...there are side effects but is doable. I feel fortunate that I am tolerating treatment as well as I am. I might not be as lucky with the next tx. Are you er/pr positive...then you could try the hormonals. Best of luck to you and keep us posted
Warmly,
Judiek
History
Discovered lump Sept. 2002 (mammo didnt pick it up)
Dx Oct 2002-just turned 41
IDC and pagets disease, stage 2B, grade 3/3, nottingham scale 9/9
3cm, lumpectomy,clean margins
er/pr-pos, her2 neg, 2/25 nodes w/cancer
Nov 2002-March 2003-FEC (5fu, epirubicin, cytoxen)
March 2003- started tamoxifen
May 2003- finished rads (33tx)
June 2003-CT/PET Scan- clear
Started 3 month check ups w/lab
Dec 2003-complete hysterectomy
Jan 2004-extensive mets, both lungs & liver(labs normal)
Jan -stopped tamoxifen
Feb CEA-23 (0-3 normal) CA27.29-66.1 (0-38 normal)
Feb 23to current-clinical trial, taxol & avastin
April 15th, -CT-significant shrinkage on all tumors/plueral effusion gone
June 8th -CT-all liver lesions decreased in size/lung mets gone
Aug 9th, -CA27.29 is 22.3, CEA is .8)
Aug 9th, 2004-Brain-CT neg, lung mets/pleural effusion still gone, liver mets had slight shrinkage. Largest hypodesne lesion is 2.1cm, 6 others 1cm or less.
Sept 13th-bone scan negative, mri revealed herniated disc.
Sept 27- Ct of brain, negative/lung mets still gone/ 2 liver lesions gone, 4 under 1cm, 1 @1.7cm.
Nov 29-CA27.29 is 24, CEA is 2.4
Nov 29-CT shows stable, lungs still clear, liver tumors stable0 -
The slow growth of liver mets was not affected favorable by femara, herceptin, nor the chemo navelbine. For a while one lesion disappeared and returned larger. Wonder where it was while growing unseen!?!Glow said:Thanks for you reply. Have been on all hormones except Fasladex. I will ask about avista. Thanks so much.
Now it can be felt somewhat enlarged but I feel not bad and do not intend to go on anything. When God wants me I'll go and that thought I can handle. But I am 67 and that makes a difference - and husbandless and childless. For many of you, much younger, it is a harder choice.
I hope I helped a little - realistically liver mets are hard to beat in the long run - any doctor will honestly tell you that.
Love and prayers, Jean0
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