This is my second go-round with breast cancer (new occurence), and I experienced menopause with the first episode 9 years ago. Now they have added Tamoxifen to my 'diet', and what little strength I had left in my vaginal lining is gone. Intercourse is out of the question, even with copius amounts of lubricant. My gyn wants me to use Vagifem, a very low dose estrogen suppository, twice a week. My oncologist wants me to use it only as a very last resort. Has anyone else experienced this degree of atrophy, and/or used any sort of vaginal estrogen following ER postive breast cancer? I am halfway through radiation and would love to think that one of these days I could resume a normal sex life.