I am having a very difficult time finding a pain medicine to work for me. As far as I know, I have NOT had what is termed "bone pain," which would be a dull, persistant ache. I have the type of pain which can only be described as sharp, stabbing pains whenever I move...very similar to wrenching or pulling muscles. At this point, my whole torso is affected as well as my shoulders. In trying to find pain relief, I have tried, Extra-Strength Excedrin, Tylenol 3, Vicodin, Fentanyl (Duragesic) pain patch, Celebrex, Motrin, Roxanol (morphine) and Ultram (opiate). The biggest problem is that NOTHING I try takes the pain away. I mean, after all, when I have a headache, I take an aspirin & it goes away, so why aren't any of these pain medications working on my muscle pain which is caused by the cancer in my bones? And whenever I try some of the stronger drugs, such as morphine, I end up vomiting for hours because of it....without ever having any pain relief. Has anyone ever had this happen to them? I am so sick of trying pain medication and not knowing whether I'll throw up or not. The oncologist's answer is just to keep prescribing more drugs in hopes that I'll find something that works.