Mixed Cellularity Hodgkins Lymphoma


i was diagnosed with Hodgkins in October 2017. i started ABVD in november and my oncologist did a scan after 4 treatments and it showed significant decrease in lymph node size and FDG uptake. i am scheduled to complete my last treatment in late April. does anyone has any experience with Mixed Cellularity Hodgkins? and if so, did it completely go away after 12th treatment? i am getting nervous as i am approaching the finish line.

Thank you 



  • lindary
    lindary Member Posts: 711 Member
    Last treatment

    I was treated for follicular lymphoma. I did 6 cycles of R-Chop followed by RICE followed by 2 years of Rituxan maintenance. Through it all I was seeing the oncology people (Dr & nurses) every 3 - 4 weeks, depending on what was going on. It wasn't until the last 2 Rituxan treatments (which were every 8 weeks) that it hit me. "I am not going to be under the microscope anymore". It seems weird to not know what my blood counts are every few weeks.  Work & family keeps me busy so my "separation anxiety" is not so bad.

  • Max Former Hodgkins Stage 3
    Max Former Hodgkins Stage 3 Member Posts: 3,721 Member
    Prognosis Excellent


    Mixed cellularity is one of the most common types of HL, the second most common of all versions of "Classic Hodgkins Lymphoma" (CHL).   There are only 5 routinely recognized versions of HL: the four 'classics," and NLPHL, the form that I had.  (Compare this to 60 subvariants of Non-HL)

    All versions of classic HL respond very well to ABVD, with complete remission (CR) rates quite high. Your oncologist was using standard protocol in testing you after 4 infusions, and the response rate sounds like it was about perfect in your case.  Since everything was moving well toward CR, it then becomes extremely likely that following all 12 infusions, CR will be the result.  But that is why so many infusions are given to begin with: to ensure that any residual cells are killed before ending treatment.

    While the finish line is in one sense a relief for everyone, in another, that last PET is always stressfull also.  Statistically, things are great, and you are where you need to be.  You have cause for optimism, and I hope all continues well for you,