CSN Login
Members Online: 9

You are here

Carbo Taxol Chemo Response outcomes for EC

cindyrk23
Posts: 12
Joined: Feb 2018

Hi - Am looking for some info on level of complete remission or shrinkage on Carbo-Taxol chemo ? There is lot of data available on FOLFOX but am not able to find lot of people who got Carbo-Taxol Chemo for EC ? If anyone had experiences ( for EC , not for other cancers ) , please kindly share . 

 

Thank you .

Deathorglory's picture
Deathorglory
Posts: 310
Joined: Jul 2013

Hello Cindy,

I got carboplatin/taxol when I was stage III (my 1st time).  I did carbo/taxol alongside radiation, then had an esophajectomy, then did a bonus course of carbo/taxol (much stronger) after surgery.  I had a complete response, but still had a recurrence a couple of years later.  The recurrence was in a lung (stage IV).  I then had folfox and herceptin.  Had another complete response and have been testing clean for over six years.  I still get the herceptin weekly.

That's the short version of my story, just the different chemo regimens.  Hope it's helpful.

 

Best Wishes,

Ed

cindyrk23
Posts: 12
Joined: Feb 2018

Hi . Thanks for sharing the info . Your story is one that gives us hope since my wife is Her2+ and hercetin is added to carbo/taxol but she is stage IV since there are 3 dots ( <1 cm ) on liver . I did note that whoever got carbo/taxol , were the stage III with Radio added and then surgery . It makes sense since in stage III , its radio & surgery that knocks the large tumor and chemo is meant to kill any potential invisible ( on scans) cancer cells in blood and surface tissues . Since my wife is IV , am concerned if carbo/taxol can give full remission .  If the liver spots go away, i want to consider surgery if the GE junction doesn't complete go away and then with herceptin maintainence she may extend her NED duration . 

South Side Steve's picture
South Side Steve
Posts: 32
Joined: Nov 2011

Hi Cindy,

I had 7 Carbo/Taxol infusions along with 25 radiation treatments prior to my Ivor Lewis surgery 6 years ago this month. My surgery pathology samples came back clear, so no additional chemo treatments were necessary. It was a long recovery, but I can do everything I did before surgery. Other than sleeping on an incline and eating smaller portions for meals, the whole ordeal wasn't as "life-changing" as feared.

Steve

cindyrk23
Posts: 12
Joined: Feb 2018

Hi . Thanks for sharing info . Am glad you are doing well , your case also gives us lot of hope . 

GeriR
Posts: 20
Joined: Dec 2017

Hi. My husband had 7 rounds of carbo/taxol with 27 rounds of radiation.  Pathology after surgery showed no cancer and all lymph nodes were "clean."  That was August 2017. He has had 2 recurrences since then. He took xeloda along with radiation and is now getting Folfox every 2 weeks.  We remain hopeful. 

GeriR
Posts: 20
Joined: Dec 2017

Hi. My husband had 7 rounds of carbo/taxol with 27 rounds of radiation.  Pathology after surgery showed no cancer and all lymph nodes were "clean."  That was August 2017. He has had 2 recurrences since then. He took xeloda along with radiation and is now getting Folfox every 2 weeks.  We remain hopeful. 

siutis12's picture
siutis12
Posts: 13
Joined: Jun 2018

I had five chemotherapy sessions with that cocktail concurrently with 23 radiation treatments.  Treatment ended on June 1. I said no to the brutal surgery to remove my esophagus and reconstruct my digestive system.  I had a complete response with zero evidence of the cancer. I'm on the wait and watch program. I'm a quality of life guy.  Hoping to get 2 years of life out of this. 

PaulT
Posts: 10
Joined: Dec 2017

I had Carbo and Taxol and thought I was NED but found out from my biopsy after my surgery still showed traces of cancer cells so I was one of the ones that needed surgery. Surgery was February 2016 and have had clean scans since. Life is good. 

Deathorglory's picture
Deathorglory
Posts: 310
Joined: Jul 2013

Hello Paul,

That's great news.  I hope you continue to test clean and enjoy a pleasant/happy life for years and years!!

Best Wishes,

Ed

PaulT
Posts: 10
Joined: Dec 2017

Thank you Ed

cindyrk23
Posts: 12
Joined: Feb 2018

In my wife case , CarboTaxol didn't provide any response nor to Primary GE tumor or Liver mets. But she had allerigic reactions during infusion and lot of sideeffects. We discontinued after 2 months and started FOLFOX which provided response to her Liver mets.

midlandgigi
Posts: 7
Joined: Aug 2018

I was diagnosed with stage 2 and had Carbo/Taxol alongside radiation.  PET showed no cancer but I went ahead with Esophajectomy because it greatly increases the odds.  Pathology showed slight residual cancer but all lymph nodes were clear and I was pronounced cancer free.  Six months later PET showed ative lymph node in peritoneum. This moved me to Stage 4.   I have started Folfox with Leucovorin every 2 weeks.  I've been told there is no "cure" once the cancer is in a distant lymph node and this treatment is meant to control and contain the spread.  

I would appreciate any hints on managing the side effects of Folfox/Leuovorin.   My treatment will last 6 months if monitoring shows it is working and I can tolerate it. 

cindyrk23
Posts: 12
Joined: Feb 2018

Sorry to hear. But FOLFOX is good in clearing small distant mets and am sure in 4 months you will be cancer free. The sideeffects vary from person to person. Usually FOLFOX sideeffects are cummulative i.e initially you may experience them for few days after the infusion but as cycles add the # of days & intensity will go up. Based on the type of side effects you experience you can work out how to manage them. 

midlandgigi
Posts: 7
Joined: Aug 2018

Thanks Cindy.  Fortunately, I am mostly recovered from the surgery and am in good health other thank the eso reoccurrence.  I also have breast cancer but it is DCIS and I'm in monitoring mode with it.  No changes there in a year.

dave2018
Posts: 3
Joined: Apr 2018

I had Carbo/Taxol 5 Times (once a week) with 25 concurrent radiation treatments in May of 2018.   Subsequent pet scans and biopsies via EGD showed no evidence of cancer, but I went ahead with the surgery to remove half of stomach and half of esophagus as recommended.  GLAD I DID.  Real time pathology during surgery showed no evidence of cancer, BUT subsequent analysis of removed tissue showed rare, isolated, but poorly differentiated cancer cells in the tissue.  

Surgical recovery has been easier than I expected.  To those that wonder whether surgery is worthwhile if all looks clean, I say do it if you are otherwise in good health.

Dave

Subscribe to Comments for "Carbo Taxol  Chemo Response outcomes for EC"