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Immunotherapy Trial: Atezolizumab

slickjy
Posts: 26
Joined: Jan 2017

Has anyone had any experience or exposure to this therapy (not-yet-FDA approved for PCa) that blocks the PD-L1 pathway?  A local clinical trial is open in Phase3, testing enzalutamide in combination with atezolizumab in pateients with mcrPCa who had failed hormone therapy and not yet undergone chemo.  I have enrolled (Lupron, Zytiga have been ineffective), scheduled to start soon.  

redbelly7
Posts: 34
Joined: Jul 2017

I'm on Zytiga, how long were you on it before you knew it was ineffective?

slickjy
Posts: 26
Joined: Jan 2017

Redbelly,

4 months.  I started in late June, stopped 10/24.  PSA had gone from 48 on Sep 12th to 60 on Oct 10th.

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