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Opdivo injury

Bee1968's picture
Bee1968
Posts: 9
Joined: May 2017

Has anyone had an Opdivo injury to their kidney's? My creatinine is 3.1 and has stayed there for a month now. I saw a nephrologist he said most likely I had an acute injury to my kidney's due to Opdivo. He'd usually do a biopsy, but my platelets are below 50. 

I was just curious

po18guy
Posts: 991
Joined: Nov 2011

Frankly, since Opdivo is so new, the only source of that data would likely be kept by legal groups that are filing lawsuits against the manufacturer. It also matters how many drugs you received prior to Opdivo, how much Opdivo you received, how long since you stopped treatment with it, any other drugs received since stopping Opdivo, and if you received any radiation therapy.

Bee1968's picture
Bee1968
Posts: 9
Joined: May 2017

Thanks for the reply. I wasn't thinking of legal issues or anything. Was just wondering if anyone on here had received Opdivo and experienced a kidney injury. Mainly wanted to know how long it took their kidneys to recover.

po18guy
Posts: 991
Joined: Nov 2011

Since it is such a new drug, and since our bodies recover so differently, it will take some time for the data to emerge. I know this does not help, but long-term effects and recovery are areas in which we may have to forge our own trails through the jungle. Here is hoping that someone may be able to provide a hint.

Bee1968's picture
Bee1968
Posts: 9
Joined: May 2017

Thanks Po. 

po18guy
Posts: 991
Joined: Nov 2011

I was preparing to receive Opdivo off-label when my hematologist decided to try the TREC regimen. Fortunately, it worked perfectly and off to transplant I went.

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