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Chemo Brain

lindary's picture
lindary
Posts: 649
Joined: Mar 2015

I first saw this news story on my flipboard this morning. 

https://www.washingtonpost.com/national/health-science/when-scientists-saw-the-mouse-heads-glowing-they-knew-the-discovery-was-big/2017/05/19/f33cc574-246a-11e7-a1b3-faff0034e2de_story.html?utm_term=.cc5d0a6ab2a9

I talks about how centuries it was accept that the lymphatic system did not extend into the brain. Then 3 years ago one researcher found that they do extend into the brain. There is a lot of interesting bits in this article. As I red it I couldn't help but wonder if this would also explain the side effect known as chemo brain.

 

po18guy
Posts: 994
Joined: Nov 2011

Of all chemotherapy drugs, only methotrexate (and likely its cousin Pralatrexate) are known to cross the blood-brain barrier. Thus, it does not seem to be directly caused by the drugs themselves. Theories abound from it being a form of PTSD, to perhaps a result of the chronic lowered blood counts during chemo to...??? Still, it will be interesting to see how research pans out.

lindary's picture
lindary
Posts: 649
Joined: Mar 2015

Several times in the article they say that the research has just started. It sounds like the researchers are very excited about what new things they may find. 

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