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Clinical Trial Failure

Max Former Hodgkins Stage 3's picture
Max Former Hodg...
Posts: 3328
Joined: May 2012

I don't think anyone at the Board has mentioned bieng part of this, but it is important to be aware of, especially members with T-cell issues. 

max

http://www.foxnews.com/health/2016/07/08/juno-cancer-study-halted-after-patient-deaths.html

 

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po18guy
Posts: 1011
Joined: Nov 2011

Strange demographic - 20 somethings, and a strange dynamic in the unpredicted and undesireable side effect. I had fludarabine and Cyclophosphamide as conditioning for my transplant (it is SOP at Fred Hutch) and nearly everyone I know maintains that I survived it. This is a huge blow to the trial, but the data, morbid as it is, will certainly help to guide future trials. However, going to a less effective conditioning regimen seems only to guarantee worse overall results. A true catch-22 and sadly, part and parcel of research.  

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