Adoptive T Cell Therapy

I just learned about this today.  The way these articles talk,  this is going to be all the rage in the world of refractory/relapsed lymphoma.  Has anyone ever heard of re-engineered T-cell therapy and,  if so,  what have you heard about it? 

 

http://www.medscape.com/viewarticle/830742

 

 

Comments

  • Max Former Hodgkins Stage 3
    Max Former Hodgkins Stage 3 Member Posts: 3,721 Member
    No

    Liz,

    I have never heard of the therapy mentioned in your link. You mentioned PoGuy on another thread. For T-Cell-specific treatments, he is the man at this board.  I recall him mentioning that he has been through I believe around 18 different drugs in batteling his own disease. A person cannot get more experienced than that !  T-Cell disease is very rare, and requires an oncologist with specialized focus for the best outcomes.

    If you have not communicated with PoGuy on these threads, I recommend that you use the private e-mail feature to write to him directly,

    max

  • Liz888
    Liz888 Member Posts: 14

    No

    Liz,

    I have never heard of the therapy mentioned in your link. You mentioned PoGuy on another thread. For T-Cell-specific treatments, he is the man at this board.  I recall him mentioning that he has been through I believe around 18 different drugs in batteling his own disease. A person cannot get more experienced than that !  T-Cell disease is very rare, and requires an oncologist with specialized focus for the best outcomes.

    If you have not communicated with PoGuy on these threads, I recommend that you use the private e-mail feature to write to him directly,

    max

    T-cell therapy is for B-cell lymphoma

    Weird, huh?

    Researchers reported that 90 percent of children and adults with ALL who had relapsed multiple times or failed to respond to standard therapies achieved remission after CAR T-cell therapy. Another study showed similar results when treating children and young adults (aged 1-30 years) with relapsed or refractory ALL or non-Hodgkin lymphoma (NHL). Other CD19- and CD20-directed CAR T cells have also been shown to induce complete remissions for patients with some types of non-Hodgkin lymphoma, including diffuse large B-cell NHL, as well as advanced heavily pretreated and high-risk chronic lymphocytic leukemia (CLL).

    https://www.google.com/url?sa=t&source=web&cd=8&ved=0ahUKEwjki_GLhvPJAhWGLmMKHSBEC9EQFgg5MAc&url=https://www.lls.org/sites/default/files/National/USA/Pdf/Publications/FS27_CAR%20T-Cell_FactSheet_FINAL.pdf&usg=AFQjCNHCCr0lzv176mrpt-2i-LcbSgylHw&sig2=5hpuNFTvb0HqweOL2891FQ