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Nexavar (Sorafenib) for RAF mutation please help

javier_garcia123
Posts: 28
Joined: Nov 2014

I need to know how good is Nexavar (Sorafenib) at targeting RAF1 mutation, I ask this because Mom used Foundation One, have this mutation, and one of three Targeted Therapies recommended is Sorafenib, the other two being Regorafenib and Trametinib

 

 

The mutation is related to cell division pathway called the MAPK path: MAPK>RAS>RAF>MEK>CCNE1

 

 

 

Also, how to avoid as much as we can nausea? and if you can tell the most frequent side effects in practise and ways to avoid them

 

 

Primary cancer is unknown mucinous adenocarcinoma but Sorafenib is recommended, people use it on this forum, that's why the question here

 

 

 

Many thanks in advance for any help

 

angec's picture
angec
Posts: 923
Joined: Mar 2012

Hello, sorry about your mom.  I am not sure about your question, however, please go to www.smartpatients.com. Join and post your questions there, they have lots of I formation about most everything.  All the best!

javier_garcia123
Posts: 28
Joined: Nov 2014

Just subscribed there, trying to see which is the main forum to ask the question, if you can suggest one let me know

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