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oxaliplatin allergic reaction and desensitizing
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May 06, 2013 - 8:45 pm
I went this past Friday for my 7th treatment. I had all of the pretreatment cocktails all was good. Then the oxaliplatin and lucavorin was hooked up and within minutes I was in full on allergic reaction mode. I had hives throat closed chest tight sweats blood pressure dropped. Benadrly and epipen administerEd and a trip to the hospital via ambulance. I'm ok now but I missed my treatment and I now have to go to hospital for next treatment and try it again there. This time over 6-8 hrs very slowly got see if my body ca handle it that way. The call it desensitizing Has this happened to anyone else and has it worked? |
Joined: Jan 2013
Wow!
I am so sorry to hear about your adverse reaction to our 'friend' (yeah, right) Oxaliplatin.
I am happy to say that I have NOT had a reaction, and with only one to go, I am hoping not to.
It must have been terribly scary for you, especially when your throat closed.
I pray that your next treatment will work well for you.
Blessings! SUE
Joined: Mar 2013
Yes...I had to have the desensitizing #7 and #8.....
I had a bad allergic reaction to oxy and they had me on benadryl, steroids, and tagamet(or one of the stomach meds) the day before. Then they infused me slowly 2%, 20%, then the remainder. It does take 6-8 hours counting the premeds time. They did get the oxy in those 2 treatments and I didn't Have an allergic reaction. Best of luck to you and any questions, please ask...~ Ann
Joined: Feb 2013
Thanks. I'm nervous about
Thanks. I'm nervous about getting the next treatmentbut nit willing to give up. I hope this works ! Ill keep you posted.
Joined: Mar 2013
Actually I was really nervous ......
they did mine in the regular infusion center but they watched me carefully and didn't leave me alone at all. The doctors knew I was there and were ready if anything happened. I was ok except the normal oxy side effects. ~ Ann
Joined: Jan 2012
I also had an allergic
I also had an allergic reaction to oxaliplatin. I switched to oxaliplatin from cisplatin because I had an allergic reaction to the cisplatin with hives and sinus swelling. We tried it again with premeds but I still reacted so I switched to oxaliplatin. I used prednisone 12 and 6 hours before infusion, then got Benadryl and saulumedral at the infusion clinic before chemo. (I'm also allergic to decadron). The first infusion of oxaLiplatin was uneventful. I went for my second infusion and things seemed fine. I was aware I wasn't feeling that good during the infusion but I thought it was just from Benadryl and steriods. I got almost all the way through the infusion when I started having a reaction. I got red and itchy and then started wheezing. More Benadryl and steriods and I was feeling better. But, my oncologist says no more platinum for me.
I will have to go through desensitizing in the future if my cancER comes back again. I know a few people who have done in hospital 24 hour infusions of taxol successfully after an allergic reaction to it. Good luck.
Joined: May 2013
Anaphylaxis
Yes, I had a similiar reaction. I was on my 6 treatment when I went into anaphylaxis with the oxaliplatin. They ended up removing it from my chemo cocktail and I was fine for the remainder of my treatments. Good luck!
Joined: Jun 2012
Reaction
My son reacted badly to Lipoplatin today, badly is an understatement, he almost died, I'm still coming to terms with the shock, it closed a treatment option for us so now chemo is not an option for him, Lipoplatin has a very low toxic profile but we are all unique. Be careful ouththere folks...