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Irrotecan - extreme fatigue

Vickilg's picture
Posts: 281
Joined: Jan 2011

Last Monday I had my first full dose of irrotecan and I have been extremely fatigued.   I get chemo on Mondays and usually by Thursday or Friday I am pretty much normal but this week I just couldn't make it.  It's Tuesday and I'm still tired.  Not looking forward to starting this again on Monday.  

PhillieG's picture
Posts: 4912
Joined: May 2005

I've been on that for a long time. I've found that the day after it I'm fine, even sort of "up", then the next day I could easily become a cat and sleep all day. I get treatment on Wednesdays so I don't miss much work and have the weekend to regroup. I've also had many times where I can function normally the entire time. Being that you're "new-ish" at this protocol I'd listen to your body and follow it's lead.
After all, it's chemo not coffee...

Sundanceh's picture
Posts: 4408
Joined: Jun 2009

I was fatigued much of the time when I did this, Vicki...

Glad your platelet counts are soaring so treatment can continue...here's hoping for positive response to the treatments...that stuff does shrink tumors.


Posts: 2215
Joined: Oct 2011

its rough stuff. I usually had to deal with nausea and late on set diarhea as well as fatigue. I usually didnt start to feel really good until about a week and a half after treatment. Just in time for the next round LOL. 

Keep fighting. You have come a long way.

geotina's picture
Posts: 2123
Joined: Oct 2009

When George was on this drug, he also suffered from extreme fatigue.  The greater problem for him was the diarrhea.   The only thing you can do is take naps when needed during the day and go to bed early.  The two side effects we were warned about were the fatigue and diarrhea so grab a pillow, coverlet and declare yourself queen of the remote control.  This is a tough drug but does work very well so be kind to yourself.

Take care - Tina


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