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manwithnoname
manwithnoname CSN Member Posts: 402
edited January 2013 in Colorectal Cancer #1

Might help some folks here.

http://www.asco.org/ASCOv2/Meetings/Abstracts?&vmview=abst_detail_view&confID=114&abstractID=100408

"  Paradoxically, none surgical CR patients (n= 16) enjoyed 100% 5-year relapse free survival compared to 42% of surgical patients "

 

Comments

  • manwithnoname
    manwithnoname CSN Member Posts: 402
    #2
    This needs bumped

     Too important I think...

  • pete43lost_at_sea
    pete43lost_at_sea CSN Member Posts: 3,900 Member
    #3
    i think you are correct bump bump bump

    hugs,

    Pete

    ps its a part of the navy protocol

  • richls
    richls Member Posts: 54
    #4
    I don't understand...

    Can someone spell it out in laymens terms? Are they saying it is better not to have surgery?  Or is only better with a certain kind of chemo that is combined with 5/fu. These studies are very confusing if your not a doctor. Information that you can't understand is pretty useless for an average guy like me. They should have a cancer treatments for dummies book, lol.

  • pete43lost_at_sea
    pete43lost_at_sea CSN Member Posts: 3,900 Member
    #5
    richls said:

    I don't understand...

    Can someone spell it out in laymens terms? Are they saying it is better not to have surgery?  Or is only better with a certain kind of chemo that is combined with 5/fu. These studies are very confusing if your not a doctor. Information that you can't understand is pretty useless for an average guy like me. They should have a cancer treatments for dummies book, lol.

    my take is to take one celebrex a day

    i'll let tony translate. these tabs are pretty blue and white stripes, they must be good for me.

    hugs,

    Pete

  • richls
    richls Member Posts: 54
    #6
    pete43lost_at_sea said:

    my take is to take one celebrex a day

    i'll let tony translate. these tabs are pretty blue and white stripes, they must be good for me.

    hugs,

    Pete

    lol pete!

    Is celebrex an over the counter drug?

  • manwithnoname
    manwithnoname CSN Member Posts: 402
    #7
    richls said:

    lol pete!

    Is celebrex an over the counter drug?

    My take on it

    Print this paper and take it to your oncologist, then come back on here and tell us what they said.

    FYI my son is on 400mg Celecoxib daily. It's not over the counter.

  • Lovekitties
    Lovekitties CSN Member Posts: 3,364 Member
    #8
    richls said:

    lol pete!

    Is celebrex an over the counter drug?

    Script required in the US

    Here is a link to an article from 2011 regarding use:

    http://www.reuters.com/article/2011/05/11/us-celebrex-cancer-idUSTRE74A5SB20110511

    It seems to be fairly unbiased, giving the pros and cons.

    Marie who loves kitties

  • LivinginNH
    LivinginNH CSN Member Posts: 1,456 Member
    #9
    pete43lost_at_sea said:

    my take is to take one celebrex a day

    i'll let tony translate. these tabs are pretty blue and white stripes, they must be good for me.

    hugs,

    Pete

    :)

    :)

  • manwithnoname
    manwithnoname CSN Member Posts: 402
    #10
    Lovekitties said:

    Script required in the US

    Here is a link to an article from 2011 regarding use:

    http://www.reuters.com/article/2011/05/11/us-celebrex-cancer-idUSTRE74A5SB20110511

    It seems to be fairly unbiased, giving the pros and cons.

    Marie who loves kitties

    very interesting

         I still believe CSCs are more of a threat. Not advocating long term drug use, Celecoxib is/was used in a protocol.

     

    The study will use a unique combination drug therapy of Capecitabine (a chemotherapy drug) and Celecoxib (an FDA approved arthritis medication) to “wake up” and to “kill” colon cancer stem cells. The treatment works by activating cancer stem cells that hibernate during chemotherapy—a chief cause of treatment failure—so they can be destroyed. The proper sequence is necessary to consistently kill the dormant cells. The ADAPT concept was proposed by Drs. Lin and Linheng Li, a prominent stem cell biologist.

    It is a very powerful drug combination with good preliminary results. Pilot studies have shown significantly increased survival rates compared with conventional therapy. Of 124 treated patients, 40% of those treated with this protocol achieved complete remission or near remission with a median survival of 93.7 months and only 1/3 of the patients had surgical removal of the metastasis. The average length of survival for stage IV colorectal cancer patients on conventional treatment is about 20-24 months and 46 months for complete responders.

     

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