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target drug or chemo drug

Posts: 72
Joined: Feb 2012

I asked Texas_Wedge this question but I think you did not see it on the thread about nexavar side effects starting. You have alot of info and knowledge about this subject, so am passing the question by you again. Do you know the difference between a target drug(Votrient) and a chemo drug (Nexavar)? Thanks

Texas_wedge's picture
Posts: 2798
Joined: Nov 2011

adobe, please don't imagine I'm any kind of expert. I'm just a fellow patient who likes to poke about a bit in the hope of finding useful or simply interesting info. I'm sorry I missed your question - these threads are now so active that if you blink the one you were looking at has become number ten on the list! Also your question was embedded in the middle of the messages which are not necessarily chronologically organised and I've been out for a while at an acrimonious special golf club meeting where the entire club committee was sacked on a vote of no confidence!

Sorafenib (Nexavar is the brand name) and pazopanib (Votrient) are both biological targeted agents. The older, chemo agents in this area are things like ifosfamide (Mitoxana) and doxorubicin (Adriamycin). Votrient is actually the latest in this bunch of six recent molecularly targeted agents. It's usually better tolerated than the others. However, human bodies are the most chemically complex entities in the known universe and we differ so much biochemically that drugs have often wildly different effects on different people and there's an art of trial and error in finding the best agent/combination of agents for each individual.

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