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yippee another quiver in the bow - they say omeage-3 fatty acids reduce premature death rsik by up to 85%

pete43lost_at_sea's picture
pete43lost_at_sea
Posts: 3908
Joined: Nov 2010

but who really cares ? just harping on about that same crazy health stuff i have been on about since getting here.

i do.... thats who. my colorectal surgeon advised this soon after surgery.
i wonder if he was aware of all the benefits of good old fish oil.

been drinking this vile life saving oil for years but upped the dosage since i joined colorectal stage 3 club.

got the october 2011 life extension mag today, great article with the title of this post.
studies prove its actually anti cancer reduces rectal cancer polyps.

fish oil reduces anxiety and stress. i wonder if cancer increases these ?

getting the balance between omega-3 and omega-6 fights inflammation

fight hard, fight smart and live. PM me if you want an email of the mag to read this article.

do some research if your interested! I did. got to go and have my night time pills and potions. SAMe, cimetidene.

hugs,
pete

JimInPDX
Posts: 11
Joined: Mar 2011

>PM me if you want an email of the mag to read this article
Sorry, but how is this done?

pete43lost_at_sea's picture
pete43lost_at_sea
Posts: 3908
Joined: Nov 2010

hugs,
pete

Buckwirth's picture
Buckwirth
Posts: 1272
Joined: Jun 2010

Fish Oil Reduces Effectiveness of Chemotherapy

"Don't use these products"

Professor Emile Voest, a medical oncologist at UMC Utrecht, supervised the research. "Where resistance to chemotherapy is concerned, we usually believe that changes in the cancer cells themselves have occurred. Now we show that the body itself secretes protective substances into the blood that are powerful enough to block the effect of chemotherapy. These substances can be found in some types of fish oil. Whilst waiting for the results of further research, we currently recommend that these products should not be used whilst people are undergoing chemotherapy."

tanstaafl's picture
tanstaafl
Posts: 1292
Joined: Oct 2010

Blake, this guy's broad statements sound remarkably premature, overgeneralized, biased and unscientific, almost like a paid hit, or negative advertisement about a potential problem, perhaps easily preventable.

An interesting preliminary finding based on some preclinical tests is then transformed into a sweeping denunciation that indiscriminately equates several platinum drugs with chemotherapy broadly. The paper itself apparently notes that secretion of a resistance factor was not the case with other non platinum chemotherapy drugs tested. Perhaps the current generation platinum drugs are the primary problem.

Now we show that the body itself secretes protective substances into the blood that are powerful enough to block the effect of chemotherapy
Sounds like the body simply attempts to protect itself from extremely noxious [platinum] drugs.

These substances can be found in some types of fish oil.
Small amounts of a much lower molecular weight oil like PIFA with 16 carbons (C16) vs EPA(C20) and DHA(C22), easily separated by simple operations like distillation, occur in some fish (which kind of fish, tropical/cold/deep water, where?) Easily avoided with concentrated EPA/DHA supplements. Would we ever hear if a vegetable oil had twice as much of a similar minor oil?

Whilst waiting for the results of further research...
like similar promises of honest tobacco company research in the 1950s through the 1990s?

we currently recommend that...
"we", perhaps simlar to honoraria, prize, grant, swank dinner grubbing MD "oncology researchers" that I've personally seen in their practices, and later, acting subservient to a marketer of oncology pharmaceuticals.

these products should not be used whilst people are undergoing chemotherapy.
"Pls buy our product blindly while the price is still high"??? I've seen papers that indicate reasonable success and compatibility of fish oil with other chemotherapies - sounds like mostly platinum drugs' problem.

from the Cancer Cell paper's abstract:
blocking central enzymes involved in the production of these PIFAs (cyclooxygenase-1 and thromboxane synthase) prevents [platinum drug activated] MSC-induced resistance.
You mean aspirin, some of the natural COX inhibitor compounds, or a cheap generic like dipyridamole might prevent even the platinum drug activated problems ??? Hmmmm.

Perhaps we should look unfavorably on "researchers" and articles that start with an interesting finding and then launch into what appears to be wholesale (anti)competitive panic mongering for potential contraindications of very limited scope.

Buckwirth's picture
Buckwirth
Posts: 1272
Joined: Jun 2010

What possible economic harm is there from a substance used in conjunction with?

It would equate to coffee growers fear mongering over milk.

They have found a link, and recommend erring on the side of caution. This is reasonable science, not anti-competitive hogwash.

tanstaafl's picture
tanstaafl
Posts: 1292
Joined: Oct 2010

The articles sensationally overstate the preclinical science results in several ways. Unnecessary delays can cost lives, and often do. Scare mongering is the opening bell to the "never let a crisis go to waste" type of bad governance.

... erring on the side of caution???

Here's a fish oil and carboplatin trial of real people with lung cancer:

"...Experimental studies have shown that supplementation with fish oil (FO) can increase chemotherapy efficacy without negatively affecting nontarget tissue. This study evaluated whether the combination of FO [fish oil] and chemotherapy (carboplatin with vinorelbine or gemcitabine) provided a benefit over standard of care (SOC) on response rate and clinical benefit from chemotherapy in patients with advanced NSCLC."[lung cancer]

"RESULTS: Patients in the FO group had an increased response rate and greater clinical "benefit compared with the SOC group (60.0% vs 25.8%, P = .008; 80.0% vs 41.9%, P = .02, respectively).
The incidence of dose-limiting toxicity did not differ between groups (P = .46).
One-year survival tended to be greater in the FO group (60.0% vs 38.7%; P = .15)."

"CONCLUSIONS: Compared with SOC, supplementation with FO [fish oil] results in increased chemotherapy efficacy without affecting the toxicity profile and may contribute to increased survival."
------------------
Erring on the side of caution to me may mean buying triple concentrated fish oil and taking 1/4 (40 mg) to 1/2 (80 mg) of an aspirin. As done since last year.

The practical result of any confirmed PIFA (C16) concern would be an improved quality spec on fish oil distillation to remove oils less than C18 when they are eliminating any possible PCB and Hg traces.

pete43lost_at_sea's picture
pete43lost_at_sea
Posts: 3908
Joined: Nov 2010

a truly amazing study which is positive for fish oil.

i just enjoyed reading the lef article. i have been doing so many supplements not stopping either. but when i get a good report about what i am doing i want to share it, then everyone can do research if they want too. some may benefit hopefully.

hugs,
pete

pete43lost_at_sea's picture
pete43lost_at_sea
Posts: 3908
Joined: Nov 2010

i was not aware of this caveat with fish oil and chemo.
at the same site was a positive article about fish oil and weightloss during chemo.

for those of us in survivorship, fish oil was many potential benefits.

for those on chemo, well arguments for and against.

whats valuable here is the discussion , patients can make their own choice.

they don't call it an essential fatty acid for no reason.

hugs,
pete

Fish Oil Fights Weight Loss Due to Chemotherapy
ScienceDaily (Feb. 28, 2011) — A new analysis has found that supplementing the diet with fish oil may prevent muscle and weight loss that commonly occurs in cancer patients who undergo chemotherapy. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the study indicates that fish oil may help combat cancer-related malnutrition.

LivinginNH's picture
LivinginNH
Posts: 1458
Joined: Apr 2010

Hi Pete, please be very careful with fish oil! Did you tell your oncologist that you're taking it? Rick's oncologist told him to stop it immediately since it could cause a brain bleed when taken along with chemo. Best wishes, Cynthia

pete43lost_at_sea's picture
pete43lost_at_sea
Posts: 3908
Joined: Nov 2010

been finished folfox 5 months now, no plans for more chemo anytime soon god willing.
i bought my box of supplements in once and showed onc, she had a fit on the spot. only joking. been on fish oil and heaps of supplements the whole way.

as i said my colorectal surgeon recommended it. i guess it depends on our individual chemo and onc. not the first time difference opinion between onc and surgeon.

i hope rick is going well.

hugs,
pete

yoga
Posts: 87
Joined: Feb 2011

Hello!
Seems like there are differing views here. My naturopath - a doctor of naturopathy who treats only cancer patients - recommended Omega 3 and as I have many allergies I am on Salmon Oil. This was one of the few things that my first oncologist gave me the 'okay' to take. My second oncologist has supported all of my supplements and has encouraged me to continue researching - I will, of course, check with my naturopath and oncologist before adding something else.
Decisions . . . decisions . . . will they ever end?!?
yoga jo

pete43lost_at_sea's picture
pete43lost_at_sea
Posts: 3908
Joined: Nov 2010

decisions decisions THEY WILL NEVER END.
well not until we do.
which i hope is a long long time.
hugs,
pete
ps i'd be intersted in your onc and naturopaths feedback if you care to share.

marqimark's picture
marqimark
Posts: 242
Joined: Jun 2011

I am not taking fish...yuck!

mark

pete43lost_at_sea's picture
pete43lost_at_sea
Posts: 3908
Joined: Nov 2010

to be honest i hate the taste.
but every morning i take a swig of pure fish oil from a bottle in the fridge.
much more concentrated than most of the otc capsules.

if you don't like fish oil, have you considered grinding your own flaxseeds by anychance.
I do every morning as well and have these live a little no fat yogurt and blueberries and other seasonal fruits. yes my whole dam diet is anticancer.

the point here is you can get omega 3 from other sources besides fish oil. its what my vegan friends do.

hugs,
pete

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