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Short Course of Hormone Therapy Boosts Prostate Cancer Survival

mrspjd
Posts: 694
Joined: Apr 2010

Short Course of Hormone Therapy Boosts Prostate Cancer Survival: Study
Coupled with radiation, six months of treatment improved odds in locally advanced cases, researchers found.

http://health.usnews.com/health-news/family-health/cancer/articles/2011/03/25/short-course-of-hormone-therapy-boosts-prostate-cancer-survival-study

The study is published in the March 24 online edition of The Lancet Oncology:

http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(11)70063-8/fulltext

mrspjd
Posts: 694
Joined: Apr 2010

Another interesting article and study on this subject:

Hormone Deprivation Ups Prostate Cancer Survival
http://www.medpagetoday.com/HematologyOncology/ProstateCancer/27532

More details about the study:

Radiotherapy and Short-Term Androgen Deprivation for Localized Prostate Cancer
http://www.nejm.org/doi/full/10.1056/NEJMoa1012348

VascodaGama's picture
VascodaGama
Posts: 3078
Joined: Nov 2010

Finaly the real results. Neoadjuvant HT proves its benefits. I wonder if the protocol of HT included a solo agonist or a solo anti-agonist or both.

VG

mrspjd
Posts: 694
Joined: Apr 2010

VG,

Take a look at this link. It should answer your question.

http://clinicaltrials.gov/show/NCT00002597

Best,

mrs pjd

VascodaGama's picture
VascodaGama
Posts: 3078
Joined: Nov 2010

It seems they used both in the whole period of four months. Two months as neoadjuvant (debulking)plus two as adjuvant.

Regards
VG

VascodaGama's picture
VascodaGama
Posts: 3078
Joined: Nov 2010

I think it wise to add in this thread the benefits found in a Canadian study in administering HT in short cycles of Intermittent Periods which were found to be as good as in longer (continuous) administered periods. Shorter times on the drugs means lesser time under the side effects, therefore, improved quality of live.
Here is the link;

http://www.pcf.org/site/c.leJRIROrEpH/b.7633981/k.3C11/Intermittent_Androgen_Deprivation.htm

The Best to all the “crew” on this boat.

VGama

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