topotecan/irinocan

Hi again, anyone had either of these with any success, or know of anyone that had success? I am torn between the two. My US doc is saying topo (although he says irinocan is very much the same thing) and my Japanese doc is saying irinocan, but if I want topo then that is basically the same thing. I think, translated they are saying, "It's all a crap shoot!", right?

I have not read any accounts from anyone personnally that had success with topo (or my brain can't recall anyway) but I did read a couple stories where irinican did work for a while.

Any input welcome,
kathleen