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Can I drink alcohol with Fluorouracil (5-FU) and Leucovorin?

CessnaFlyer's picture
Posts: 110
Joined: Aug 2009

I enjoy one or two glasses of wine in the evening and perhaps a martini once a week in the afternoon. I’ll be starting Fluorouracil (5-FU) and Leucovorin this Thursday and will have the injections once a week for six weeks and then I will have two weeks off. Should I totally give up alcohol during the entire treatment period, or just the day I receive treatment?

grammadebbie's picture
Posts: 432
Joined: Jun 2009

Hi Cessna Flyer,

Welcome to this forum. It's a great source of encouragement and information. I'm sorry that I don't have an answer for you. I'm sure someone knows and will reply. Everyone is different though so be sure and check with you doctor. Let us know how you're doing and if you have any questions.

Blessings to you,

Debbie (gramma) there is another Debbie here so I added gramma

Posts: 63
Joined: Jul 2009

Hi my husband was told by two onc. at different hospitals that he can have a drink on occasions but they did not mention if he can have it on the days of the chemo. However, although he was a beer drinker he has quit since diagnosed 15 months ago.

hoagiemom's picture
Posts: 87
Joined: Feb 2007

When I first started chemo I asked my onc nurse if it was ok to drink a glass of wine during treatment. He told me not to because the liver was filtering the chemo out of the body and you don't want your liver to work harder. Now I do know some people who would drink beer or wine but I didn't for the 6 months of treatment. I honestly didn't feel like drinking because nothing tasted the same for me when I was on chemo. Now 2 years out and I do have my glass of wine on Friday evenings.. Michelle

shrevebud's picture
Posts: 106
Joined: Aug 2009

Hi Cessna:

I too like wine and drank a little every now and then while I was on chemotherapy. Sometimes I drank a few glasses. I didn't drink anything stronger than that. I have liver involvement so I think about those effects more than drinking during treatment. Right now I'm off treatment and don't have any desire to drink anything. Chemotherapy is known for making people unusually tired and sometimes interfering with thought processes - the alcohol might add to those effects. Nausea might be another concern. If you keep it in moderation you're probably fine. Your onc. might advise against it though. Everyone's different. If you feel good and want some wine, I'd say have some. Take care. Roy

PhillieG's picture
Posts: 4912
Joined: May 2005

I would have a beer here and there but after my first operation (I did 6 months chemo then surgery) I did not drink for quite a while. My Onc is a strictly NO person but the nurses told me one or two here and there would be OK. I wouldn't drink every night, but that's me. If your liver has been compromised I wouldn't think it would be great for it.
Smoke mj instead!

PamPam2's picture
Posts: 376
Joined: Jan 2009

Hi. I tried drinking a couple times when on chemo, didn't work for me. Made me feel terrible, and gave me pretty bad diarreah. Now, even several years later, alcohol doesn't hit me well, maybe that's a good thing.

daydreamer110761's picture
Posts: 497
Joined: Dec 2008

all I can say is that I did, but not on treatment days. I didn't have really much trouble as far as nausea goes, but I would drink wine up until the Sunday before treatment, start treatment on Tuesday thru Thursday, and Thursday or Friday night have more wine. On a few occasions I actually had a cocktail or two (vodka/cranberry for me).

My Onc had said that it was ok to have a few, but as others said preferred me to not drink during treatment because of the liver involvment. Somebody else mentioned the taste, and I did notice that as treatment progressed, the wine just didn't taste as good as it used to, but it still helped me sleep.

ldot123's picture
Posts: 276
Joined: Apr 2008

My oncologist said drinking might mess up my blood work when checking out liver functions plus in general thought it was not a good idea - sorry to say.

Cheers, Lance

mommyof2kds's picture
Posts: 522
Joined: Mar 2009

My oncologist advised no alcohol.

2bhealed's picture
Posts: 2085
Joined: Dec 2001

hi flyer,

Cancer loves to feed on sugary stuff and alcohol is a simple carb turning right into sugar so basically you're feeding your cancer when you drink. Alcohol is also acid producing and cancer loves that too.

When one has cancer it makes sense to starve the sucker...the cancer not the host. So why push it? Why not wait until the cancer is good and gone just to be on the safe side.

Instead why not try a veggie juice cocktail (carrots, celery, ginger, kale, apple etc etc) of fresh organic veggies that actually can help you heal from cancer. Try it, you may like it!

Just a thought.

peace, emily

Dyanclark's picture
Posts: 296
Joined: Apr 2012

Great comment. I'm Dyan's husband,George(with crc). Thanks for the advice,Emily!

thxmiker's picture
Posts: 1282
Joined: Oct 2010

My Oncologist at UCLA said no issue with having a drink or two a night. Dr. Lenz at USC said zero alcohol because Chemo is already such a task on the Liver, that the alcohol makes it that much harder to get well.

Best Always, mike

PS I did have a glass or two of wine during chemo and it kicked my hiney. I did not drink during the infussion nor the pump days. Day three or four until I started Chemo again I had a glass or two of red wine.

maglets's picture
Posts: 2596
Joined: Jun 2006

just saying this is an old thread.....read the dates...


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